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Biomedical subjects

R Hilf

Publications and source records attributed to R Hilf.

At least 181 records · Page 10Linked to original sources
PubMed1968

Hormonal dependence of DNA synthesis in mammary carcinoma cells in vitro.

Explants of C3H-mouse and rat R3230AC mammary carcinomas were cultured on chemically defined medium for study of the effects of the hormonal environment on synthesis of DNA. Synthesis in the more slowly proliferating C3H carcinoma cells is stimulated by insulin and inhibited by estrogenic hormones as in normal mammary epithelial cells. Rat R3230AC mammary carcinoma cells can initiate synthesis of DNA independently of insulin or estrogenic hormones. Autonomous growth with respect to these hormonal controls correlates with rapid proliferation, but it is not an essential characteristic of the neoplastic mammary cell.

Adenocarcinoma↗
PubMed1967

Milk-like fluid in a mammary adenocarcinoma: biochemical characterization.

The milk-like accumulation in the R3230AC mammary adenocarcinoma that follows treatment with estrogen contains lactose, fatty acids, and proteins with electrophoretic properties similar to those of casein and whey of rat milk. This mammary tumor retains the biochemical capacity of the mammary gland in its lactational response to administration of hormone.

Adenocarcinoma↗