PubMed Health⌕ Search

Biomedical subjects

R Hinder

Publications and source records attributed to R Hinder.

4 recordsLinked to original sources

Altered antroduodenal motility after cholecystectomy.

BACKGROUND: Persistent nonspecific symptoms such as epigastric pain, bloating, nausea, and bilious vomiting are common following cholecystectomy. The etiology of these symptoms is unknown, but abnormal antroduodenal motility associated with duodenogastric reflux (DGR) is a possible cause. PATIENTS AND METHODS: Sixteen postcholecystectomy patients and 19 healthy volunteers ("normals") were studied. Ten of the patients were asymptomatic and 6 were symptomatic. The study consisted of a 4-hour 99mTc-DISIDA (diisopropyl imidodiacetic acid) infusion and gastric aspiration, 24-hour intragastric pH monitoring, and 24-hour ambulatory antroduodenal manometry. RESULTS: The postcholecystectomy patients showed increased DGR of the infused 99mTc-DISIDA. The data are given as coulter counts x 10(6)/min. The increase was more marked in symptomatic postcholecystectomy patients (2.54 +/- 0.15) compared to asymptomatic patients (1.21 +/- 0.46) or normals (0.26 +/- 0.15). Postcholecystectomy patients had increased percentage of time with intragastric pH > 3. In the supine period in particular, the pH was > 3 in symptomatic patients 25.4% +/- 7.7% of the time versus 8.1% +/- 4.3% for asymptomatic patients (P < 0.01). The antral phase III frequency after cholecystectomy was 2.5 +/- 0.09 cycles/min compared to 3.2 +/- 0.08 cycles/min in normals (P < 0.0001). Furthermore, propagation of the phase III front in the duodenum was significantly slowed to 0.14 +/- 0.02 cm/s after cholecystectomy compared to 0.27 +/- 0.02 cm/s in normals (P < 0.001). The duration of phase III in the proximal duodenum after cholecystectomy was also decreased to 4.3 +/- 0.27 min compared to 5.9 +/- 0.35 min in normals (P < 0.005). CONCLUSIONS: Fasting antroduodenal motility is altered after cholecystectomy. The abnormality is associated with increased DGR, which is more marked in symptomatic patients.

Adult↗

Thoracoscopically assisted esophagectomy with gastric pull-up for esophageal cancer.

Thoracoscopically assisted esophagectomy with gastric pull-up was done in a 56-year-old man with esophageal cancer. The thoracoscopic technique, including the use of intraoperative ultrasound, is discussed. The addition of thoracoscopy offers safer and more complete esophageal dissection than transhiatal blunt esophagectomy and is less invasive than conventional thoracotomy.

Adenocarcinoma↗

Open laparoscopy for laparoscopic cholecystectomy.

This report deals with the first 350 laparoscopic cholecystectomies performed at Creighton University, beginning in October 1989, by one of the authors (R.J.F., Jr.). An open technique was used for initial access to the abdominal cavity in 343 patients (98%). Patients included 274 females and 76 males, with an average age of 45.5 years. Weight ranged from 72 to 316 pounds (32-142.2 kg). The laparoscopic procedure was successfully completed in 338 (96.6%). Operative cholangiography was performed in 113 (32.3%), and 52 (14.7%) had acute cholecystitis as determined by the final pathological report. Median operating time was 80 min. There was no operative mortality. Bile duct injury was not seen. Postoperative complications occurred in 21 patients (6%), only two of which were directly related to the open technique (cellulitis of the umbilical wound requiring antibiotics). A third patient (0.3% of 343 successful laparoscopies) required reoperation on postoperative day 4 for a small bowel perforation; the exact cause could not be determined, but conceivably it was related to the umbilical minilaparotomy. We conclude that the open technique is safe and effective method for initial peritoneal access prior to laparoscopic cholecystectomy.

Adolescent↗