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Biomedical subjects

R Hobson

Publications and source records attributed to R Hobson.

8 recordsLinked to original sources
PubMed1992

Femoral pseudoaneurysm from drugs of abuse: ligation or reconstruction?

A plan for management of infected arterial pseudoaneurysm has evolved from our experience with 23 such aneurysms treated between 1981 and 1989 and followed for up to 66 months. Eighteen femoral artery aneurysms are the primary focus of this report. Because we were concerned about the high probability of amputation expected from acute interruption of the femoral artery, we were reluctant to limit initial management to ligation and debridement alone. However, significant complications developed in 12 patients who underwent revascularization, requiring 3 amputations and 13 secondary arterial operations in addition to debridements and skin grafts. In contrast, no amputations were required in six patients who underwent primary arterial ligation and debridement. We recommend primary ligation that controls the septic focus, removes the danger of hemorrhage, and is not accompanied by the threat of secondary arterial infection. After ligation, limb viability is assessed during surgery by presence of an audible Doppler signal at the ankle. Revascularization is considered only when absence of a Doppler signal indicates acute limb ischemia.

Adult↗
PubMed1990

Seasonal koilonychia in Ladakh.

During a health survey for chest disease in Ladakh, it was noted that women and a few men had marked koilonychia. It caused disfigurement, discomfort and sometimes disturbance of function. It occurred mainly in spring and summer and usually disappeared in winter. It is thought to be due to exposure to cold wet mud while repairing walls and irrigation canals. There was no evidence of iron deficiency.

Adult↗
PubMed1988

Prediction of post cataract extraction visual acuity: 10 Hz visually evoked potentials.

Cataract patients suspected of having disease that might interfere with good postoperative visual function were evaluated by eliciting monocular steady-state luminance visual evoked potentials (VEPs) with closed eyes at a stimulus rate of 10 flashes/sec. VEPs were rated as either normal or abnormal. Patients with normal VEPs were predicted to have visual acuity of 6/15 (20/50) or better. Patients with abnormal VEPs were predicted to have acuities of 6/18 (20/60) or worse. Postoperative acuities were determined for all patients who underwent surgery and who had no intraoperative or early postoperative complications. The predicted and observed postoperative acuities were quantitatively compared for the 59 patients who met these criteria, using a 2 X 2 contingency table. The chi-square was significant (p less than .001). The overall accuracy of prediction was 80%. Accuracy of the predictions for patients with preoperative acuities of 6/60 (20/200) or better was compared with the accuracy of the predictions for those with preoperative acuities of 60/120 (20/400) or worse. There was no significant difference (p greater than 0.10).

Cataract Extraction↗
PubMed1987

Pattern electroretinogram: effects of reference electrode position.

The pattern electroretinogram has assumed greater clinical and experimental significance because of its inner retinal origins. However, clinical tests may be confounded by an artifact. We tested subjects varying reference electrode position and eye stimulated while employing the Dawson-Trick-Litzkow (DTL) fiber electrode as the active electrode. The presence of a statistically significant artifactual response could not be confirmed. However, the variability of responses elicited with the outer canthus was less and the signal-to-noise ratio greater than with other reference positions.

Analysis of Variance↗
PubMed1987

10-Hz flash visual evoked potentials predict post-cataract extraction visual acuity.

Cataract patients suspected of having disease which might interfere with good postoperative visual function were referred for evaluation. Monocular steady-state luminance visual evoked potentials (VEPs) were elicited with closed eyes at a stimulus rate of 10 flashes/sec. VEPs were rated as either normal or abnormal. Patients with normal VEPs were predicted to have an acuity of 6/15 (20/50) or better. Patients with abnormal VEPs were predicted to have acuities of 6/18 (20/60) or worse. Postoperative acuities were determined for all patients who underwent surgery and who had no intraoperative or early postoperative complications. The association of preoperative VEPs and observed postoperative acuities were quantitatively compared by a 2 x 2 contingency table for the 59 eyes which met these criteria. The chi-square was significant (p less than 0.001). The overall accuracy of prediction was 76%. Accuracy was 80% for patients with a preoperative acuity of 6/60 (20/200) or better and 75% for those whose postoperative acuity was 6/120 (20/400) or worse. This difference was not statistically significant.

Cataract Extraction↗