[Developing countries: new directions in health policy].
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Developing Countries↗
Biomedical subjects
R Hoppler
Publications and source records attributed to R Hoppler.
[Developing countries: new roads in healthy policy].
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Developing Countries↗
[Post-transfusion hepatitis 1973 and 1974 in the Zürich region].
More than 100 000 units of blood were tranfused during the years 1973-74 in the region of Zurich. 30 cases of posttransfusion hepatitis (PTH) reported in this period were investigated with regard to the origin of the tranfused blood, and 24 (71%) proved to be hepatitis B antigen (HBS-Ag) positive. Despite the use of a sensitive method for HBS-Ag screening, transfusion of HBS-Ag positive blood was found to be responsible for PTH in 4 cases only. In 88% of the cases there was no proof that the PTH was caused by blood transfusion. Hepatitis A virus, EPstein-Barr virus and Cytomegalovirus do not appear to be important causative factors in PTH syndrome. Reasons for failure to detect hepatitis virus in donor blood are discussed. There appear to be other sources of hepatitis-virus infection than blood transfusion.
Hepatitis↗
[Microaggregates in preserved blood].
Today it is generally accepted that microaggregates contained in stored blood may be deleterious to the pulmonary circulation if large volumes of blood are transfused. These microaggregates can be eliminated from blood with the help of microaggregate filters. Such filters are expensive and their efficiency and safety has not been tested thoroughly as yet. Alternatively, the use of microaggregate-free blood is advocated to prevent pulmonary complications in massively transfused patients. Fresh blood, fresh frozen plasma and buffy-coat free red cell concentrates do not contain significant numbers of microaggregates and can be used for massive transfusion without microaggregate filtration.
Blood Platelets↗