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Biomedical subjects

R Hudson

Publications and source records attributed to R Hudson.

8 recordsLinked to original sources
PubMed1978

Saint Augustine's College training program in industrial hygiene and safety.

The Occupational Safety and Health Program at St. Augustine's College leads to a Bachelor of Science degree in Industrial Hygiene. This program enables the students to enter careers in practice and research in industry and government or to pursue graduate studies. The curriculum in industrial hygiene provides a broad academic foundation during the first two years of college, after which, students proceed with advanced studies in industrial hygiene and supporting courses in the natural and behavioral sciences. St. Augustine's College industrial hygiene and safety curriculum course descriptions are presented and other aspects of the program are discussed.

Curriculum↗
PubMed1977

Lymphocyte-like cells of the tunicate, Pyura stolonifera: binding of lectins, morphological and functional studies.

In vitro investigations were carried out to determine whether lymphocyte-like (small round) cells of the tunicate Pyura stolonifera react to allogeneic cells and mitogens in a manner comparable to that of vertebrate immunocytes. The lymphocyte-like cells possessed receptors for concanavalin A, wheat germ agglutinin and soybean lectin as shown by binding of radioiodinated lectins in scintillation counting and autoradiographic assays. This binding did not induce mitogenesis. Mixtures of cells of P. stolonifera individuals taken from the same or distinct localities did not show enhanced DNA synthesis when assayed at time intervals ranging from 3 to 10 days. The small round cells of this and other tunicates are not completely similar to vertebrate lymphocytes in morphology. Our observations support the concept that these cells are not directly homologous to immunologically competent vertebrate lymphocytes, but may serve as haemopoietic stem cells as proposed by other (Endean, 1954; Freeman, 1970).

Animals↗
PubMed1977

Rapid antibiotic disk sensitivities of burn eschar and infected wounds.

This study was undertaken to develop a more rapid antibiotic sensitivity test of the pathogens in soft tissue infections and burn wound eschar. The proposed rapid antibiotic sensitivity test was performed directly on the clinical specimen rather than on single strains of bacteria isolated from the tissue. By performing the antibiotic sensitivity tests directly on the tissue sample, the physician obtains the test results within seven hours after receiving the specimen rather than 38 to 52 hours later, the time delay encountered with the conventional technique. The modification used did not alter most of the standards advised by the Food and Drug Administration (3), since there was no inclusive change in medium, agar depth or antibiotic sensitivity disk. The changes in the Kirby-Bauer (1) test necessitated by using the clinical specimen did not alter significantly the interpretation of the antibiotic susceptibility. If clinically significant numbers of bacteria, 10(6)-10(9), were present, variations in the inoculum size did not appreciably change the results of the antibiotic susceptibility tests. If the incubation requirement for the standard Kirby-Bauer (1) antibiotic susceptibility test was reduced to seven hours, it also did not significantly limit the accuracy of the test. As expected, the variable most difficult to standardize was the heterogeneous inoculum containing large numbers, 10(7), of different organisms. A zone of inhibition interpreted as sensitive with one organism was occasionally masked by the presence of the confluent growth of an organism in which the zone of inhibition was considered resistant. However, even in this instance, it is possible that mixed culture sensitivities may provide the most valid information in mixed infections, since they more closely simulate the real clinical situation.

Anti-Bacterial Agents↗