Biomedical subjects

R Hultgren

Publications and source records attributed to R Hultgren.

3 recordsLinked to original sources

PubMed2005

Gender differences in patients treated for critical limb ischemia.

OBJECTIVE: To investigate, in patients treated for critical limb ischemia, how pre-operative conditions, localisation of lesions and outcome varied according to gender. DESIGN: Retrospective cohort study. METHODS: Medical records were analysed for all patients treated with vascular reconstruction or PTA for critical limb ischemia 1993-1994 (119 women, 115 men) at the Karolinska Hospital. All events such as secondary intervention, amputation and death occurring until 2003 were included in the analysis. RESULTS: The preoperative conditions were similar between women and men apart from higher mean age (74 years in women vs 69 in men, p=0.0002), fewer subjects with a smoking history (63 vs 82%, p=0-005) and diabetic disease (22 vs 43%, p=0.0004) among females. More interventions were performed suprainguinally in women (44% in women vs 19% in men). Amputation and survival rates were similar in women and men, even after matching for age and diabetes. CONCLUSION: Women were older, had a lower frequency of diabetes, smoked less and had more proximal lesions than treated men. Outcome was identical for both genders. Biological and anatomical differences could possibly explain several of the found gender differences. Gender differences in risk factors and possibly in the selection process also may have contributed to our findings.

Aged↗

PubMed2001

Gender differences in vascular interventions for lower limb ischaemia.

OBJECTIVES: to investigate changes in intervention for lower limb ischaemia with regard to gender. MATERIAL AND METHOD: type of procedure, the age and gender of all patients (8687) undergoing interventions (12 295) for lower limb ischaemia in Stockholm 1970-1994, were obtained from the National Board of Health and Welfare. RESULTS: interventions rose from 18 per million inhabitants in 1970 to 786 in 1994. The proportion of women treated grew from 34% to 48%. The number of embolectomies decreased from 80 to 69 per million. Infrainguinal reconstructions increased most from 38 in 1980-1984 to 186 per million inhabitants in 1990-1994, with the proportion of women increasing from 33 to 43%. Mean age increased from 63 to 71 years. CONCLUSIONS: there was a marked increase in the number of procedures, the proportion of female patients and mean age.

Age Factors↗

PubMed1999

Sexual function in women suffering from aortoiliac occlusive disease.

OBJECTIVE: To describe the sexual function in women suffering aortoiliac occlusive disease (AIOD) and in an age-matched reference group. PATIENTS AND METHODS: Thirty-six women suffering from AIOD were included. Twenty were investigated before vascular intervention (untreated) and 16 different women after treatment (treated). Eighteen age-matched women served as a reference group. The patients answered a questionnaire including sexual, social and medical questions and a gynaecological examination was performed. RESULTS: Untreated patients with AIOD have a significantly impaired physical well-being compared to the other groups (p < 0.001). A negative effect of the vascular disease and its treatment on sexual life was experienced by 69% of treated compared to 40% affected among untreated (p = 0.05). Vulval sensibility was impaired in 44% of treated, 11% of untreated and 22% of reference patients. Defective anal sphincter function was found in 33% of treated, 17% of untreated and 6% in the reference group. Those differences were not statistically significant. CONCLUSIONS: Symptomatic AIOD in women is associated with a significantly impaired physical and sexual well-being. Though limited by size and methodology, the results indicate the possibility of iatrogenic nerve damage.

Adult↗