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Biomedical subjects

R I Vagner

Publications and source records attributed to R I Vagner.

At least 91 records · Page 5Linked to original sources

[Combination of primary lung cancer with extrapulmonary carcinomas].

An analysis is given of 50 observations of lung cancer associated with cancer of other organs. Lung cancer was preceded by cancer of another organ in 33 patients (66%), cancer of another organ developed after lung cancer had been cured--in 6 (12%), and synchronous involvement was noted in II (22%). An average interval between radical surgery for lung cancer and subsequent tumor growth in another organ was 6.2 years. Among patients with synchronous carcinomas the association with laryngeal cancer (4) and cancer of the stomach (4) was most frequently noted. The principles of treatment in patients with synchronous carcinomas are described.

Adult↗

[Importance of mediastinoscopy and parasternal mediastinotomy in the accurate determination of the operability of lung cancer patients].

The authors give a comparative estimation of the results of 217 mediastinoscopies, 58 parasternal mediastinotomies, performed in 274 patients with pulmonary cancer to determine precisely their operability. Positive findings in mediastinoscopy were noted in 66 (33.4%) of 217 patients, especially in cancer of median localization (in 42 of 153 patients or in 32%) and of the right lung predominantly (in 51 of 134 patients or in 45.5%). Parasternal mediastinoscopy yielded positive findings in 30 (51.7%) of 58 patients. This method proved to be mostly reliable in examining patients with peripheral bronchus cancer, especially in left lung localization of the tumor. The results of mediastinoscopy and parasternal mediastinotomy are similarly conditioned by the morphological structure of the tumor. Due to mediastinoscopy and parasternal mediastinotomy 57 (26.6%) of 222 patients, previously referred to as being "operable," proved to be inoperable. These methods also would aid in avoiding tentative thoracotomy or nonradical surgery in 78 (30.7%) of 254 patients, primarily considered to be "operable" or "doubtfully operable".

Adult↗

[State of circulating blood volume, blood components and the function of external respiration in lung cancer].

The data concerning the changes in the circulating blood volume, globular and plasma volumes, red blood cells indices and also some indices of the external respiration function in lung cancer cases are set forth. Radiopneumography has permitted to find out some significant disorders in the regional ventilation and in the pulmonary blood flow in early postoperative period, which in case of hypoventilation is likely to cause a severe respiratory insufficiency and, therefore, requires an energetic therapeutic control.

Adult↗

[Importance and prospects of surgical study methods in lung cancer].

More than 20 years' experience with surgical exploration in cancer of the lung is generalized in this article. The use of prescalene biopsy allowed to find out metastases in 130 out of 308 patients (42.2%), mediastinoscopy helped to refine the degree of the propagation of the process in 36.2%, and parasternal mediastinotomy--in 49.5%. Due to laparoscopy and laparotomy metastases in the abdominal organs (liver, adrenal glands, retroperitoneal nodes) were found in 22 out of 162 patients. The diagnostic thoracotomy carried out upon 109 patients revealed tumors of the lungs in 50 patients, in 47 out of them it was an early stage of primary cancer.

Biopsy↗

[Evaluation of the surgical and combined treatments of lung cancer].

Ninety six patients with lung cancer metastasizing in regional lymph nodes were clinically examined by randomization method. A half of these patients was subjected only to surgical treatment, the other half was given postoperative radiotherapy. The comparison of the results of the combined and solely surgical treatment of lung cancer patients indicated a greater survival in irradiated patients.

Adenocarcinoma↗

[Use of laser impulses in the treatment of melanoblastoma of the skin].

Favourable results of the treatment of skin melanoblastoma by means of pulse laser radiation are reported in 34 patients and of melanoblastoma skin metastasis in 13 patients. The follow-up lasted up to 5 years. There were no cases of local relapse. Metastasis in the regional lymph nodes were found in 5 patients (17%). Before the start of the treatment the latters had not shown any metastasis.

Adolescent↗