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Biomedical subjects

R Iffland

Publications and source records attributed to R Iffland.

At least 37 records · Page 2Linked to original sources

[Methanol and isopropanol as markers of alcoholism].

Car-drivers, who lost their licence on account of drunkeness, must be tested if the danger of alcoholism exists. The only criterion for this check is the level of bloodalcohol during this case. This check happens mostly one year later. It is proposed to analyse the blood sample immediately after measuring bloodalcohol for markers of chronic or acute abuse to differ alcoholics from persons consuming alcoholic beverages in normal mode.

1-Propanol↗

[Do bacteriologic-chemical drinking water studies of households with suspected SIDS have significance?].

In 30 households with SIDS the drinking-water was studied microbiologically and chemically regarding its bacteriological contents, also it was checked for Pb and Cu. Three test solutions of 45 bacteriologically researched samples revealed significant data. One sample showed 2400 cfu "colony forming unit" which is more than double the number of germs permissable in an drinking-water container according to the standards of drinking-water (TrinkwV) 1(3). Also Ps. aeruginosa were found. A further sample contained 3300 cfu Coliforme (E. cloace in 100 ml). The lower quality of a further samples with 2.6 x 10(6) cfu could be retrospectively explained by works done by the Berlin City Works (Berliner Wasserwerke). Enteric bacteria could not be revealed. The remaining 42 samples were within the criteria Section 1 [(1), (2), (3)] of the drinking-water standard. Samples which fulfilled the norms of Section 1 (3) TrinkwV for reserve containers with up to 1000 cfu can be explained by the known fact that water in pipes (containers) can easily be contaminated from outside, for instance through germs like Pseudomonades. In none of the samples a connection between water quality and bacteriological post-mortem findings could be found. In two groups concerning the research for heavy metal the amount of Pb did not surpass the limit of drinking-water standards. In several cases the amount of Cu surpassed that of Pb. Bacteriological-chemical water research in households with suspicion of SIDS are only useful if anamnestical, clinical and autoptic data can be brought into a close temporary and spatial order and if the findings can be controlled through repeated research.(ABSTRACT TRUNCATED AT 250 WORDS)

Bacteriological Techniques↗

[Methanol, isopropanol, n-propanol--endogenous formation affected by alcohol?].

Methanol, isopropanol and n-propanol are detected usually in blood samples during the determination of congeners. The ethanol-induces formation of methanol and isopropanol has been described formerly. Also little amount of n-propanol were detected in blood, which could not be reduced to the alcoholic beverages.

1-Propanol↗

[Ethanol and isopropanol consumption].

Drinking tests with isopropanol or isopropanol and ethanol, in which blood levels were measured over some hours, have not yet been described in literature. Pharmacokinetic parameters like decomposition rate, distribution volume or distribution factor were calculated. The results of these tests are discussed also in their reliance to clinical treatment of intoxications.

1-Propanol↗

[Optimizing carbon monoxide detection in biological material].

The determination of the CO-content is difficult in heated or putrified samples of blood and tissues. The preparation of these materials and a sensitive gas-chromatographic detection of small amounts of carbon-monoxide with head-space technique are described. The iron-content of a sample is a measure for the complete saturation with carbon-monoxide. This content is measured with AAS in the same vessel used before to determine CO. The presented method is suited too for ecological studies.

Carbon Monoxide↗

[Therapy and clinicotoxicologic follow-up of tartar emetic poisoning caused by an ant insecticide in a small child].

Since some years lindane has been replaced by tartar emetic in a sweet tasting liquid against ants, of which a three year old girl drank nearly 50 ml containing 2.3 g tartar emetic. This is a multiple of the lethal dose for children. But this child survived. The course of the intoxication and its therapy are described. The levels of antimony were controlled in blood and urine.

Antimony↗