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Biomedical subjects

R Ikram

Publications and source records attributed to R Ikram.

3 recordsLinked to original sources

A case control study to determine risk factors for campylobacter infection in Christchurch in the summer of 1992-3.

AIM: This study was designed to determine the risk factors for acquiring campylobacter infection in Christchurch in the summer of 1992/3. METHODS: A case control study was conducted of 100 cases and controls from urban areas matched for age and sex. Cases and controls were interviewed by telephone using a questionnaire and results analysed using the Epi Info statistical computer programme. RESULTS: Eighty one percent of both cases and controls had recently consumed poultry. Eating poultry at a friends house (OR = 3.18, CI 1.0, 10.73, p = 0.03), at a barbecue (OR = 3.00, CI 0.99, 9.34, p = 0.03) or eating undercooked chicken (OR = 4.94, CI 1.03, 23.62, p = 0.05) was a risk whereas eating at home was protective (OR = 0.36, CI 0.14, 0.9, p = 0.02). Other factors associated with increased risk were drinking water from a nonurban supply (OR = 2.7, CI 0.89, 8.33, p = 0.09) or consumption of chicken bought fresh (OR = 1.8, CI 0.85, 3.82, p = 0.10). CONCLUSION: Poorly cooked or handled chicken is a significant source of human campylobacter infection. Morbidity may be reduced by increased public awareness and improvement of cooking practices.

Adolescent↗

Epstein-Barr virus infection acquired from a cadaveric renal transplant.

A 42-year-old man, seronegative for Epstein-Barr virus (EBV), received a cadaveric renal transplant. Serology from the 27-year-old male donor indicated an active EBV infection. Following treatment for acute rejection with OKT3 the recipient developed a severe systemic illness. Clinical features strongly suggested an acute EBV infection and serology showed seroconversion for EBV. The patient died and autopsy histology revealed widespread polymorphic lymphocyte infiltration in lymph nodes and solid organs. To our knowledge this is the first report of a kidney being transplanted from a donor who was subsequently shown to have had EBV infection at the time of organ retrieval. The EBV status of an organ donor should be considered more frequently.

Adult↗