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Biomedical subjects

R J Helfman

Publications and source records attributed to R J Helfman.

7 recordsLinked to original sources
PubMed1985

Grover's disease treated with isotretinoin. Report of four cases.

Grover's disease (transient acantholytic dermatosis; TAD), a disorder of unknown etiology, may resemble Darier's disease and frequently resists conventional therapies. The lesions can be extensive and pruritus can be a prominent feature. Four patients with Grover's disease were treated with isotretinoin. Three patients with relatively acute disease responded with remissions of up to 10 months after treatment. One patient with disease of 8 months' duration obtained partial relief but experienced a relapse when medication was stopped.

Acantholysis↗
PubMed1985

Reticulated porokeratosis. A unique variant of porokeratosis.

A young man presented with a chronic, persistent reticulated dermatosis involving the groin, genitals, and thighs that was refractory to therapy. Biopsy specimen revealed multiple cornoid lamellae consistent with porokeratosis. This clinical appearance has not been previously described, to our knowledge. The other clinical forms of porokeratosis and their histology are briefly reviewed.

Adult↗
PubMed1984

Isotretinoin dermatitis simulating acute pityriasis rosea.

A pityriasis rosea-like eruption developed in two acne patients receiving isotretinoin and gradually resolved once the dosage was reduced. Histologically the lesions, which were characterized by psoriasiform hyperplasia, bore no resemblance to pityriasis rosea. We believe the eruptions were a side effect of isotretinoin therapy.

Acne Vulgaris↗
PubMed1983

Photodermatitis multiformis acuta.

A condition precipitated by acute sun exposure, occurring primarily in women, and having all the characteristics of erythema multiforme is reported.

Acute Disease↗