Biomedical subjects
R J Marsh
Publications and source records attributed to R J Marsh.
Ophthalmic zoster.
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Ocutome lensectomy: results and complications.
We describe the results and the complications encountered in 69 lensectomies performed via a limbal approach with the Ocutome vitrectomy instrument, in which it was the intention at surgery to maintain the integrity of the posterior capsule. After operation 87% improved in visual acuity, and 68% achieved 6/12 or better. The main early complications encountered were perioperative rupture of the posterior capsule and iris damage. The main late complications were postoperative thickening of the posterior capsule, retinal detachment, and bullous keratopathy. Of the eyes in which the posterior capsule remained intact after operation 17% developed thickening of the posterior capsule to a degree that required capsulotomy over a mean follow-up period of 50 months.
Ophthalmic herpes zoster.
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Cine photography and video recording of anterior segment fluorescein angiography.
A description is given of apparatus and technique for carrying out cine photography and video recording of anterior segment fluorescein angiography. We found cine best for single-frame analysis and video tape recording less expensive.
Patch testing in ocular drug allergies.
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External ocular motor palsies in ophthalmic zoster: a review.
Seventy-seven new patients suffering from ophthalmic zoster and a selected group of 69 old patients were carefully examined with regard to external ocular movements. An incidence of 31% of ocular pareses was found in the new patients, and 58 in all were analysed. We were surprised to find several of these were contralateral and bilateral palsies. 28% of the palsies were asymptomatic, due to diplopia being present only in extremes of gaze and the rapid development of suppression in the affected eye. The theories of aetiology of these pareses are discussed.
Herpetic corneal epithelial disease.
The clinical differentiation of corneal epithelial lesions due to herpes simplex or herpes zoster may be confusing. Practical clinical tests, including the use of topical ocular stains, are useful to differentiate corneal epithelial lesions caused by these two viruses. Two distinctive types of zoster corneal epithelial disease may be seen; an early dendritic form, and a delayed form characterized by corneal mucus plaques that may take a dendriform pattern. These plaques are composed of mucus that is adherent to swollen, degenerating epithelial cells. The clinical differentiation between these two viruses is essential since topically applied corticosteroids are contraindicated in epithelial herpes simplex and often are indicated in the management of epithelial herpes zoster.
Current management of ophthalmic herpes zoster.
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Phenolization of bladder in treatment of massive intractable hematuria.
Intractable hemorrhagic cystitis secondary to radiation or cyclophosphamide (Cytoxan) therapy could lead to serious complications; however, intravesical instillation of phenol has reduced the dilemma of this life-threatening problem. We present a case of intractable hemorrhagic cystitis secondary to cyclophosphamide therapy treated with 100 per cent phenol with no untoward side effects. Since formalin instillation into the bladder has been associated with severe complications, phenol appears to be safer and more effective in the treatment of intractable hematuria, and, therefore, its clinical trial is recommended.
Treatment of senile macular disease.
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