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Biomedical subjects

R J Martini

Publications and source records attributed to R J Martini.

4 recordsLinked to original sources

[Recurrent bacteriuria in children].

Fifty-four children admitted to the Children's Hospital of Cordoba City with recurrent bacteriuria were followed for 12 to 97 months. Most of them were females and Escherichia coli was the most frequent microorganism isolated in recurrent attacks of bacteriuria. Ninety percent of the patients showed urological abnormalities. Vesicoureteral reflux was the most frequent. Residual urine was considered the main cause of recurrent bacteriuria. After antibioticotherapy and surgical treatment, over one half of the patients persisted with relapses. Recurrent bacteriuria appeared more frequently in male infants with severe urologic abnormalities. Finally, three groups of patients in relation to uropathy and functional renal impairment are described and a different prognosis for each one is proposed. For this reason, each patient must have a complete urologic examination done at the onset and a carefull follow-up, carried out.

Bacteriuria↗

[Longitudinal study in children with the nephrotic syndrome and minimal glomerular lesion].

Twenty-one children with idiopathic nephrotic syndrome and minimal changes on renal biopsy were followed during all the disease. The average of follow-up was 37 months, with a range from 12 to 124 months. Recurrent proteinuria was the most important feature during the follow-up; 14 out of the patients showed frequent relapses, but only 2 patients showed major complication (peritonitis, septicemia) during relapses. Frequent relapses appeared most frequently in patients who began the disease before their fourth birthday, showed allergic history, had hypertension and red blood cells in urine, or had recurrent infections and finally, in those where proteinuria reappeared soon after prednisone therapy was ended. Prednisone alone was successful to induce remission, but it did not prevent frequent relapses. The association clorambucil-prednisone allowed lengthening of the period of remission and possibly for this reason the rate of relapses fell during the first 37 months of the follow-up. There are no signs which permit to predict the length of the disease and the frequent relapses can occur even after many years from the beginning of the disease. Special care of these patients avoids major complications.

Biopsy↗