The Bulgarian anomaly: demographic transition and current fertility.
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Bulgaria↗
Biomedical subjects
R J McIntyre
Publications and source records attributed to R J McIntyre.
Isolation and characterization of myelin-related membranes.
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Animals↗
Kinetic studies on the hydroxylation of p-coumaric acid to caffeic acid by spinach-beet phenolase.
1. A spectrophotometric assay is described that enables the hydroxylation of p-coumaric acid to caffeic acid, catalysed by spinach-beet phenolase, to be followed continuously. 2. Initial-velocity and inhibitor studies indicate that the order of substrate addition is oxygen, p-coumaric acid and electron donor, with an irreversible step separating the binding of each substrate. 3. Caffeic acid is most likely to act as electron donor at the active site; other electron donors, such as ascorbic acid, NADH and dimethyltetrahydropteridine, function mainly to recycle cofactor amounts of caffeic acid. 4. A reaction scheme, consistent with these data, is proposed.
Ascorbic Acid↗
The action of hydrogen peroxide on the hydroxylation of p-coumaric acid by spinach-beet phenolase.
Treatment of spinach-beet phenolase with H2O2 under aerobic conditions results in a stimulation of the p-coumaric acid hydroxylation it catalyses, but not the caffeic acid oxidation. Spectroscopic evidence suggests that an oxygenated enzyme species is formed under these conditions.
Caffeic Acids↗
Pronatalist programmes in Eastern Europe.
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Demography↗