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Biomedical subjects

R J Nicholson

Publications and source records attributed to R J Nicholson.

7 recordsLinked to original sources

Human blood pressure and pulse rate response to racemic epinephrine retraction cord.

1. The pulse rate of patients after application of racemic epinephrine-impregnated retraction cords depends more on the level of anxiety and stress than on the level of the epinephrine. 2. Blood pressure is elevated by placement of racemic epinephrine-impregnated retraction cords upon an exposed vascular bed or lacerated tissue. 3. Four percent racemic epinephrine-impregnated retraction cords cause less elevation of blood pressure than 8% racemic epinephrine cords. 4. Although the elevations in blood pressure from 8% cord occur within a narrow range, this range may be hazardous to cardiac patients. Therefore, 4% racemic epinephrine cord should be used. 5. A desirable amount of tissue retraction is produced by 4% racemic epinephrine cord. 6. Dry cords do not provide adequate retraction of tissue and are contraindicated for tissue-retraction purposes.

Adult

Direct and indirect pulp capping.

Cavity disinfection, indirect pulp capping, and direct pulp capping have been discussed in light of present day knowledge of the biology of the pulp. A format has been presented to the restorative dentist which has had long-standing clinical acceptance based on some scientific data and clinical evidence to substantiate the treatment radionale.

Calcium Hydroxide

Comparison of tissue response between a synthetic gutta-percha and a natural gutta-percha endodontic filler.

Biologic acceptance is one of several criteria that must be met by an endodontic filling material. The purpose fo this experiment was to compare a new filling material consisting of a synthetic gutta-percha with a standard material consisting of natural gutta-percha. Each sample, being an endodontic point, contained a quantity of fillers. The materials were implanted subcutaneously in male white rats. The histologic appearance was essentially identical for both materials.

Animals