PubMed Health⌕ Search

Biomedical subjects

R J Postlethwaite

Publications and source records attributed to R J Postlethwaite.

69 records · Page 4Linked to original sources
PubMed1984

Subcutaneous emphysema: a new form of self abuse.

Subcutaneous emphysema is usually the result of trauma or surgery. We report an unusual case of a disturbed adolescent who presented with cervicofacial emphysema as a result of self abuse.

Adolescent↗
PubMed1984

Continuous subcutaneous insulin infusion in diabetes mellitus. A year's prospective trial.

Thirteen children aged between 8 and 16 years were entered into a 12 month prospective trial comparing continuous subcutaneous insulin infusion with intensified conventional treatment. Two of seven children on insulin infusion withdrew after eight and nine weeks, and three of six children on conventional treatment withdrew after four to eight weeks. Withdrawals in both groups were related to dissatisfaction with the techniques. The group on insulin infusion treatment achieved a mean plasma glucose of 9.8 mmol/l (176.4 mg/100 ml), a median M value of 50 mmol/l (900 mg/100 ml) and a mean glycosylated haemoglobin of 9.1% during the year. This represents a significant improvement compared with the previous values, and also when compared with the conventional treatment group whose trial values of a mean plasma glucose of 15.5 mmol/l (279 mg/100 ml), median M value of 167 mmol/l (3006 mg/100 ml), and glycosylated haemoglobin of 10.4% were not significantly different from those before the trial. Two children on insulin infusion developed subcutaneous abscesses in the early months. There was an increased incidence of diabetic ketoacidosis in this group, but no difference in the incidence of serious hypoglycaemia between the two groups. The children reported improved well-being when using insulin infusion and continued with the technique after the trial finished. Insulin infusion offers an acceptable means of improving glycaemic control for some diabetic children.

Adolescent↗
PubMed1984

Urinary albumin excretion in school children.

Concentrations of albumin were measured by an enzyme linked immunoassay in 24 hour urine collections (divided into day and night-time samples) from 183 boys and 191 girls aged 4 to 16 years. The 24 hour albumin excretion rate and day and night-time albumin excretion rates all increased with age in both girls and boys. Albumin excretion during the day exceeded that at night in both girls and boys. Albumin excretion rates were higher in girls than boys during the day but there was no significant difference at night-time. The urinary albumin creatinine ratio showed no change with age, but was greater in girls than boys during the day and at night, and was also greater during the day than at night in both sexes. Graphs of normal values of albumin excretion rates and albumin creatinine ratios are provided.

Adolescent↗
PubMed1981

Postural deformities in congenital nephrotic syndrome.

Six successive cases of congenital nephrotic syndrome are described. Each one showed flexion deformities of the knees and hips, widely open anterior and posterior fontanelles, and wide separation of the skull sutures. These abnormalities were present not only in cases in which the renal histology was of the microcystic Finnish type of congenital nephrotic syndrome, but also in those in which the histological picture was one of the variants associated with congenital nephrotic syndrome. It is suggested that such abnormalities are postural deformities, possibly produced by the large placenta.

Abnormalities, Multiple↗
PubMed1976

Influenzavirus A2 infections presenting with febril convulsions and gastrointestinal symptoms in young children.

We present the clinical features of Influenzavirus A2 infection in 75 young children admitted to a children's hospital. The most common presenting features were febrile convulsions. vomiting, coughing, diarrhea, and anorexia. At any age, the illness may present with respiratory tract symptoms and signs but in young babies gastroinestinal symptoms are often the presenting complaint. Children aged one to three years often present with febrile convulsions. Only in older children does the adult pattern begin to emerge. Evidence is put forward to suggest that encephalitis in association with influenza can be due to direct invasion of the central nervous system by the virus.

Adolescent↗
PubMedDate not supplied

Living with chronic renal failure.

We describe our impressions gained in the process of systematic interviewing of children with chronic renal failure. In spite of improved techniques of medical treatment in recent years, many of these children and their families remain under considerable strain. This is caused by anxieties about the child's general prospects for the future, problems in accepting the illness and treatment, particularly with a late onset of the condition, and multiple hospital admissions with occasional life-threatening incidents. In spite of their less serious nature, chronic features such as poor growth and urinary incontinence seem to be particularly worrying for many children and their parents. We feel that it is worth considering how to improve the supports for these families, helping parents to be more aware of community facilities that are available, and striving to improve communication between the different agencies (hospital, general practitioners, schools, etc.) involved.

Adaptation, Psychological↗