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Biomedical subjects

R J Sigelman

Publications and source records attributed to R J Sigelman.

1 recordsLinked to original sources

Posterior amorphous corneal dystrophy.

A family of ten individuals aged 18 months to 75 years had biomicroscopic findings consisting of large, amorphous, sheet-like opacifications of the posterior stroma and Descemet's membrane, and alterations of the endothelium. A uniform thinning of the cornea was present. These findings do not conform to previously described corneal dystrophies. The condition appears minimally progressive and the three-generation pedigree indicated an autosomal-dominant inheritance pattern.

Adolescent↗