Renal peripelvic plasmacytoma: unusual radiographic findings.
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Biomedical subjects
Publications and source records attributed to R J Teears.
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The results of the 1975 CAP Comprehensive Chemistry Survey of serum magnesium are presented. More than 1,260 laboratories participated in this survey. The most commonly used method for the measurement of serum magnesium concentrations is atomic absorption spectrophotometry. Colorimetric dye methods (Rapid-Stat (TM) kits, the Dupont ACA and titan yellow) follow in popularity. Variation in precision was lowest with atomic absorption and highest with titan yellow methods. All three of the dye-binding methods demonstrated either consistently negative or consistently positive biases when compared with the weighted mean concentration. The differences between the mean concentrations obtained by the dye-binding methods and atomic absorption spectrophotometry are statistically analyzed, and several conclusions are presented. As demonstrated by this survey and at the concentrations measured, the estimation of serum magnesium by any of the commonly used methods, except titan yellow, is clinically appropriate.
Lithium data from the 1975 College of American Pathologists Comprehensive Chemistry Survey program have been analyzed. The results have been organized into five method-dependent groups: four variations on emission flame spectrophotometry, and one group containing all manual atomic absorption methods. The bias observed between flame emission and atomic absorption methods was correlated with the sample mean. In addition, three paired specimens were analyzed by mean comparison. This study indicates that atomic absorption methods have a negative bias, but an apparent correlation with the sample mean indicates the probability of standardization error between the methods. This may be related to a protein depression effect and may be due to differences in viscosity between aqueous standards and serum-based samples. Both atomic absorption and flame emission methods demonstrate variability that is clinically satisfactory.
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Clinical and pathologic features of 88 cases of carcinoma metastatic to the pituitary gland were reviewed. In 61 (69.3%), metastases were localized either in the posterior lobe alone or in the posterior and anterior lobes together; only 12 (13.6%) involved the anterior lobe alone. Diabetes insipidus was present in 6 patients (6.8%), one of whom also had clinical panhypopituitarism due to metastatic tumor and necrosis in the anterior pituitary lobe. Breast and lung were the most frequent primary sites in women and men, respectively. Sixty-four (72.7%) of these glands were grossly normal at necropsy. Metastases to the pituitary gland occur more frequently in the posterior lobe than in the anterior lobe, and my ve reflected clinically by diabetes insipidus in patients with diseminated carcinoma. Clinical panhypopituitarism is a rare accompaniment of anterior lobe involvement.
Leiomyosarcoma of the rectum is a rare neoplasm and may behave in a highly malignant manner. Our experience with a single case prompted a review of the Armed Forces Central Medical Registry (AFCMR), where six other cases were found from the total AFCMR population. Four patients were treated with abdominoperineal (AP) resection; three had local excision only. Three patients developed metastatic disease and two of those died. The authors recommend prompt wide excision (AP resection) for any case of leiomyosarcoma of the rectum.