Hydration with Ringer's lactate solution; its effectiveness in maintaining stable circulation during and after surgery.
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Biomedical subjects
Publications and source records attributed to R J Trudnowski.
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We have demonstrated sequestration of unchanged meperidine in gastric juice of humans following intravenous administration. Concentrations attained were as great as 360 times plasma concentration. The drug was first detected between 5 and 15 minutes after administration. This phenomenon appears to be due to ionization and ion trapping of meperidine in gastric juice.
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