PubMed Health⌕ Search

Biomedical subjects

R J Zochowski

Publications and source records attributed to R J Zochowski.

84 records · Page 5Linked to original sources
PubMedDate not supplied

[The effect of bretylium tosylate on ventricular arrhythmias in patients with acute myocardial infarction].

Sixty three patients with the acute myocardial infarction, aged between 34 and 85 years, admitted to the Intensive Cardiological Care Unit during the first 12 hours following the infarction were randomly divided into two groups. Patients of group I (20 subjects) were treated with nitroglycerin and additional intravenous infusions of bretylium tosylate in the dose of 5 mg/kg administered every 6 hours for 48-72 hours. Patients of group II (33 subjects) were mainly treated with intravenous nitroglycerin. A type and incidence of the ventricular arrhythmias, conduction disorders in AV node, and hemodynamic complications were analysed during the first 72 hours. It was found that bretylium tosylate reduces the incidence of ventricular arrhythmias accompanying myocardial infarction but after 2-3 hours following its administration (p < 0.05). Therefore, bretylium tosylate should be administrated to patients with the acute myocardial infarction in combination with other rapidly acting anti-arrhythmic drug. Bretylium tosylate increases also the effectiveness of electric defibrillation in patients with ventricular fibrillation or ventricular tachyarrhythmia. No evidence of the effectiveness of bretylium tosylate on atrio-ventricular conduction and hemodynamic complications of myocardial infarction was found.

Adult↗
PubMedDate not supplied

[Thrombi of the left ventricle, infarction location and method of treatment].

A study is reported of 63 patients treated in the Cardiology Department, Institute of Internal Diseases, MSW for acute myocardial infarction. They were divided into two groups: 21 patients w treated with intravenous streptokinase infusion and then with intravenous heparin, with simultaneous administration of nitroglycerin. The other group comprised 42 patients treated with nitroglycerin alone. On the basis of the mass of the infarcted tissue calculated from the curves of CK-MB levels, and echocardiography for assessment of the presence of left-ventricular clots and degree of impairment of cardiac wall contractility according to Heger a much more frequent occurrence was noted of clots in the left ventricle in patients treated with nitroglycerin only, but the volume of the infarcted tissue was not statistically significantly different between both groups.

Echocardiography↗