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Biomedical subjects

R Jaenke

Publications and source records attributed to R Jaenke.

5 recordsLinked to original sources
PubMed1987

Monitoring the progression of renal failure in a horse with polycystic kidney disease: use of the reciprocal of serum creatinine concentration and sodium sulfanilate clearance half-time.

Sequential reciprocals of serum creatinine concentration and sodium sulfanilate clearance half-times were used to monitor a horse with chronic renal failure. The horse was diagnosed as having polycystic kidney disease; at least one cyst was of distal tubular origin. Using the plots of the sequential data, a reasonably accurate prediction was made for complete renal decompensation to develop.

Animals↗
PubMed1982

Comparative cardiac and renal toxicity of daunorubicin in the rat and rabbit.

A direct comparison of the cardiac and extracardiac effects of repeated daunorubicin administration in the rat and rabbit demonstrated a basic similarity in the cardiac myocyte response. The rat, however, appears to develop a more severe drug-related nephropathy, resulting in widespread soft tissue mineralization that includes vessels and the myocardium. These findings suggest that the severity and development of acute and chronic anthracycline-induced cardiac lesions may, in the rat, be related or dependent, in part, on concomitant nephrotoxicity.

Animals↗