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Biomedical subjects

R Janson

Publications and source records attributed to R Janson.

At least 19 recordsLinked to original sources
PubMed1984

[Intrathoracic-extrapleural esophageal replacement with gastroplasty].

We carried out replacement of the oesophagus by transposing the stomach in 87 patients, 64 with carcinoma of the oesophagus. There is an immediate operative mortality of 20-30%, but this is followed by a relatively low morbidity, which is well demonstrated radiologically (stricture at the anastomosis, which can be mechanically dilated, about 22%; external fistula with a tendency to spontaneous closure about 25%; ectasia of the thoracic stomach, 15-25%). Average survival time is eight to ten months. There is a 24% risk of post-operative pulmonary oedema and daily chest x-rays are indicated.

Adult↗
PubMed1983

Segmental determination of sensory neurons in Drosophila.

The analysis of flies where one segment is transformed into another by mutation or by experimental treatment shows that the central projection of a sensory neuron depends on its segmental determination. The genetic functions that control the segmental determination of neurons and of epidermal cells appear to be distinct, but they have common regulatory features.

Animals↗
PubMed1983

[Digital video subtraction angiography of the abdominal aorta, the pelvic and leg arteries].

The arterial system can be demonstrated after intravenous contrast injection by means of DVSA. The abdominal aorta, pelvic and lower limb arteries were examined in this way in 152 patients. Occlusions, stenoses and areas of dilatation could be recognised. In 8% of the patients the aortic bifurcation or common iliac arteries were not adequately visualised. In other respects, the results of DVSA were comparable with conventional arteriography. Because of limited image size, DVSA is particularly indicated where the vascular changes can be localised accurately by clinical means. The method is well suited for observing the results of surgery or percutaneous angioplasty. The indications for arteriography have been reduced as a result of DVSA.

Angiography↗
PubMed1983

Should treatment of highly differentiated thyroid carcinoma be conservative?

On the basis of three selected cases (one with clinically occult follicular and two with metastatic papillary carcinoma) the necessity of a comprehensive therapeutic concept even in highly differentiated thyroid cancer is stressed. Thyroid tissue and regional metastases should be eliminated by surgery, followed by radioiodine therapy in any event. Radiation teletherapy should be reserved to patients with invasive tumor growth exceeding the organ capsule, with lymph node metastases, and with massive angioinvasive growth.

Adenocarcinoma↗
PubMed1982

[The value of oral gastrografin in the diagnosis of ileus (author's transl)].

One hundred and thirty examinations with oral gastrografin were performed in 110 patients with obstructive symptoms, who did not require immediate operation. They consisted of 49 patients with mechanical ileus, eighteen patients with paralytic ileus and 63 patients with incomplete mechanical ileus. All patients with complete mechanical and three patients with paralytic ileus were investigated surgically and treated in this way. Small bowel transit time longer than five hours provides considerable certainty of complete mechanical ileus. The method has been tried for four years; it makes few demands on the patient and has practically no contra-indications, except for deranged electrolyte balance. In children, the amount of contrast medium should be limited and it should be diluted or an isotonic contrast medium should be used. The method provides definite differentiation between mechanical and functional obstruction. In patients with adhesions and recurrent incomplete obstruction, further laparotomies may be avoided in this way.

Diatrizoate↗
PubMed1982

[Angiomatous dysplasia (Weber type) (author's transl)].

A rare form of angiomatous dysplasia with hypotrophy of the left arm is described. Numerous haemodynamically significant arterio-venous fistulae could be demonstrated in the soft tissues and in bone. The venous and lymphatic systems were normal. The lacunar reticular-cystic changes in the spongiosa of the phalanges are pathognomonic of arterial angiodysplasia of the Weber type. In most cases this is associated with bone hypertrophy.

Adolescent↗
PubMed1982

[Do retroperitoneal vascular abnormalities influence the operability of metastasizing testicular tumors?].

The lymphatic drainage of the testis is closely related topographically to the large retroperitoneal vessels. In retroperitoneal lymphadenectomy (RLA), the surgeon therefore takes the vessel topography as his point of orientation. Typical vascular findings, deviated from the norm, of altogether 285 lymphadenectomies (Jan. 1966-Dec. 1980) are described. The vascular variations do not influence the radicality of the operation. Knowledge of these variations help to prevent vascular lesions. On the other hand, infiltrations of larger vessels entail an extension of the operation. Involvement of the renal vessels (walling in, infiltration) may necessitate nephrectomy. Infiltrations of the wall of the aorta, vena cava or the pelvic vessels are resected and sutured according to the rules of vascular surgery. Involvement of infrarenal and unilateral renal vessels may not be allowed to impede radical extirpation of the tumor.

Adolescent↗
PubMed1982

[Bleeding intrarenal pseudodiverticulum: successful superselective embolization (author's transl)].

The article reports on a successful superselective transcatheteral embolization of a small but massively bleeding calyciform pseudodiverticulum. The tissue adhesive butyl-2-cyanoacrylate, mixed with lipiodol, was used as embolisate. This material offers the the advantage of permanent vascular occlusion and can be injected via smallest catheters, using the coaxial catheter technique. The differential diagnosis of such a calyciform pseudodiverticulum is discussed.

Adult↗