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Biomedical subjects

R Janson

Publications and source records attributed to R Janson.

At least 55 records · Page 3Linked to original sources

[Coronary calcification and luminal diameter in coronary disease (author's transl)].

Two hundred and thirty-six patients with coronary heart disease were examined by coronary angiography and laevo-cardiography. In 111 patients (47%) there was coronary artery calcification. Of these, 108 patients (97%) showed abnormal findings on the coronary angiogram; in 72 patients (67%) coronary stenosis was greater than or equal to 50% of the lumen. The severity of the stenoses increased with the amount of calcification. There were only three false positive findings and the presence of coronary calcification indicates coronary sclerosis with a high degree of probability. Fluoroscopy is the simplest and most sensitive method of examination and is of great value in the non-invasive investigation of coronary sclerosis.

Calcinosis↗

[Computer-cardio-tomography in idiopathic hypertrophic subvalvular aortic stenosis--a new contribution to non-invasive diagnosis (author's transl)].

The use of computer tomography as a non-invasive procedure in the diagnosis of idiopathic hypertrophic subvalvular aortic stenosis is described. Seven patients were investigated in whom the diagnosis had been confirmed by echocardiography and laevocardiography with pressure measurements. Details of the method are discussed and computer tomography and echocardiography are compared. The features of greatest differential diagnostic importance relating to asymmetrical septum hypertrophy are discussed.

Cardiomegaly↗

[Computer tomographic diagnosis of pericardial effusions (author's transl)].

Thirty patients with suspected pericardial effusions, or with cardiac enlargement of unknown cause were examined by computer tomography. In 19 cases a diagnosis of pericardial effusion or haematoma was made. All these cases were confirmed by echo cardiography or transthoracic puncture. The accuracy of computer tomography diagnosis did not depend on the aetiology, but could be increased by contrast enhancement. The computer tomographic criteria are enumerated and compared with those of echo cardiography. Examples of the most important differential diagnoses are discussed.

Adult↗

[Quantitative functional analysis of the left ventricle in coronary heart disease: an evaluation of current methods. I description of basic methods and definition of normal range (author's transl)].

The present work consists of an evaluation of quantitative laevocardiographic methods of analysis in coronary heart disease. An attempt has been made to find a correlation between the laevocardiographic results and the extent of coronary artery disease, heart size on a conventional chest X-ray with left ventricular end-diastolic pressure. In the first part, basic methods are described, particularly the laevocardiographic area-length-method of Dodge. The accuracy of the procedure and its statistical methods are discussed in detail.

Coronary Disease↗

[Quantitative functional analysis of the left ventricle in coronary heart disease. An evaluation of current methods. II. Correlation of results. Global and regional contractility parameters (author's transl)].

In the first part of the present paper, the basic methods for quantitative angiocardiography are described. In the second part, a variety of results are tabulated and discussed, derived from selective coronary arteriography, laevocardiography, left ventricular pressure measurements and heart size as seen on conventional chest X-rays. Various correlations have been derived from these. It was not possible to find an quantitative relationship between coronary sclerosis and myocardial function. The reason for this depends on the fact that the parameters derived from laevocardiography represent integrated global function. The significance of regional contractility is stressed.

Angiocardiography↗

[Phlebography of the testicular veins for varicoceles and their recurrences (author's transl)].

The clinical significance of varicoceles depends on their frequency and on the fact that they may produce infertility. The available operative forms of treatment are unsuccessful in about 10% of patinents. In these cases it is desirable to elucidate the very variable drainage pattern by means of transfemoral phlebography with the patient erect. The method was employed in 13 patients and demonstrated continuity of the testicular vein, or of one of its tributaries, in twelve. If the testicular vein appears to be absent, one must consider the possibility of a venous short circuit or drainage of the pampiniform plexus into the external iliac vein. In four patients out of the 13, scrotal phlebography in addition for complete definition was necessary.

Adolescent↗

[Radiation therapy for tumors of the nasal cavities and paranasal sinuses. I. Communication (author's transl)].

In the period between 1966 and 1976, a total of 53 cases with neoplasms of the nasal cavities and paranasal sinuses underwent radiological treatment. The 5-year-survival rate for all tumors of all stages amounted to 34.6%. Local recurrences appeared in 54%. The present cases are compared and analysed reviewing their special anatomic extension, clinical symptomatics, histology and classification. The radiotherapeutic proceeding is described.

Adult↗

[Sequential hepato-splenic scintigraphy with 99mTc-pertechnetate in experimental post-hepatic block (author's transl)].

Using baloon catheters in the inferior vena cava, post-hepatic blocks were produced in experimental animals. Subsequent liver perfusion scintigraphy showed marked reduction in portal flow. The significance of these findings in the diagnosis of the Budd-Chiari syndrome and its differentiation by scintigraphy from an intrahepatic block in cirrhosis of the liver is discussed.

Animals↗

[Mediastinal and pulmonary complications of the sclerosing treatment of oesophageal varices (author's transl)].

One hundred and twenty patients with oesophageal varices were seen in the surgical clinic between 1970 and 1975; 290 individual treatments with endoscopic sclerosis were carried out. The typical radiological complications in the mediastinum and lungs have been assembled. Clinically significant complications such as oesophageal perforations with large pleural effusions are separated from uni-important complications, such as minor effusions and plate atelectases. The method of conservative treatment of varices is described and the indications for it, as against other forms of treatment, are described.

Esophageal Perforation↗

[Radiological lung changes in progressive pulmonary insufficiency (author's transl)].

Chest radiographs can reflect increasing pulmonary insufficiency of shock lung. In the early and intermediate stages, there is almost pure interstitial oedema which, in the later stages becomes alveolar-interstitial. In addition one may find evidence of broncho-pneumonia. Respiratory insufficiency is due to abnormalities of perfusion and distribution and is aggravated by disturbance of oxygen diffusion. The latter is due to an increase in the alveolo-capillary diffusion distance in the presence of interstitial oedema. It was not possible to demonstrate quantitatively significant precapillary shunts greater than 25 mu.

Adult↗

[A review of the findings on chest examinations and at autopsy in surgical patients under intensive care (author's transl)].

The present paper deals with the findings on examination of the chest and at autopsy in 100 selected surgical patients under intensive care; of these 17% were post-traumatic, 55% had post-operative lung complications and in 28% there had been no trauma or previous operations. The accuracy of the radiological diagnosis was checked against the autopsy findings. Pneumonia and pulmonary oedema were the most common lung complications in all three groups, with an incidence of 59 to 82%, and were diagnosed with an accuracy of 92 to 95%. Other conditions which were looked for were pulmonary congestion, emboli and lung infarcts, pleural effusions, atelectasis, pulmonary haemorrhage or contusion and pneumothorax. The most common mis-diagnosis was in the demonstration of emboli and infarcts, where accuracy was only 64%. The difficulties in differential diagnosis of the radiological appearances due to these pulmonary complications are discussed.

Autopsy↗

[Trans-jugular retrograde portography. Preliminary communication].

Retrograde portography is carried out through a trans-jugular route. Contrary to previously available techniques of trans-juglar portography, the method does not inflict any trauma on the parenchyma or vessels. Demonstration of the portal system is achied by reserved flow through the liver sinusoids. Together with arterial hepatography and indirect splenic and mesenteric portography, the method provides additional information in various forms of pre-, intra- and post-hepatic block without submitting the patient to any additional risk.

Aged↗

[The use of the liver-spleen-scan for the diagnosis of congenital Intrahepatic cysts of the bile duct (M. Caroli) (authors transl)].

After the short review of the pathogenesis, diagnosis and therapy for congenital intrahepatic cysts of the bile-duct (morbus Caroli), reference was made to the diagnostic significance of liver scintigraphy on the basis of two casuistic reports. Liver scintigraphy permits an exact localization of intrahepatic cysts as well as information regarding the course of the hepatopathy connected with morbus Caroli. In addition, 131-J-bromsulfon scintigraphy of the liver is a simple method for controlling the patency of the bile ducts. Our observations tend to indicate that preoperative and postoperative scintigraphic controls of the liver are practical for this disease.

Adult↗