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Biomedical subjects

R Jayaswal

Publications and source records attributed to R Jayaswal.

At least 19 recordsLinked to original sources
PubMed1991

Excessive polycythaemia of high altitude. Pulmonary function studies including carbon monoxide diffusion capacity.

Pulmonary function studies were done in 21 soldiers (low landers) posted at high altitude (average height 4773 metres) for prolonged periods (average 77.09 months), who had developed excessive polycythaemia, mean haemoglobin concentration being 23.06 g/dl. Studies revealed significant reduction in diffusion capacity of lungs which gradually returned to normal on sojourn at low altitudes for 70 days. Both the degree of polycythaemia and reduction in lung diffusion capacity were much more pronounced in smokers than in non-smokers. Vital capacity did not show any difference in these subjects while forced expiratory volume in 1 sec and ratio of forced expiratory volume to vital capacity (FEV1/VC) revealed only obstructive features in smokers.

Adaptation, Physiological↗
PubMed1990

Pulmonary bullous disease in Marfan syndrome.

Two young adults with marfanoid features who had pulmonary bullous disease are presented. One a young soldier, presented with increasing dyspnoea and an enlarging large pulmonary bulla on the right side. The bulla was under tension and was operated on. The other case was a young housewife who also presented with dyspnoea, and was found to have a cardiac murmur and multiple ectopic beats on initial examination. X-Ray chest revealed bilateral pulmonary bullous emphysema. Both the subjects had many features which are accepted as forme fruste of the Marfan syndrome.

Adult↗
PubMed1989

Bilateral recurrent haemorrhagic pleural effusion in asymptomatic chronic pancreatitis.

In a case of bilateral recurrent haemorrhagic pleural effusion due to asymptomatic pancreatitis the diagnosis was suggested by the presence of amylase in the pleural fluid when other possible causes had been excluded. Abdominal computed tomography and laparotomy confirmed the diagnosis. No communications could be seen between the peritoneal and pleural space at laparotomy.

Adult↗
PubMed1989

Enlarging pulmonary histoplasmoma associated with pulmonary tuberculosis.

Histoplasmosis is not a frequently reported infection from India. Similarity of its clinical and radiological features with pulmonary tuberculosis, may cause a difficult diagnostic dilemma when the two occur together. We report a case who initially presented with cavitary lesions over right lung responding well to anti tuberculosis chemotherapy but subsequently a small opacity present over the left upper zone showed a relentless increase till it attained a massive size few years later. Operative removal and histopathological examination of the mass confirmed it to be histoplasmoma. She became sputum AFB smear positive and culture negative for a short while during this period and this is explained on the basis of previous reports.

Adult↗
PubMed1989

Malignant mesothelioma in the young (with prosthetic aortic valve an unusual association).

A case of malignant mesothelioma (MM) in a 15 year old boy is reported. He had a prosthetic aortic valve implanted in 1980 at our centre for rheumatic aortic regurgitation. Fever, weight loss and chest pain as initial symptoms suggested possibility of prosthetic valve endocarditis. Dysphagia as another initial symptom was interesting and caused further diagnostic dilemma. Role of Computerised Tomography (CT) scan in diagnosis of MM is highlighted.

Adolescent↗
PubMed1984

Comparative study of the effects of intravenous administration of aminophylline, salbutamol and terbutaline in patients suffering from reversible airways obstruction.

A study was carried out in 20 patients with reversible airways obstruction to compare the bronchodilator potency of salbutamol (250 micrograms), terbutaline (500 micrograms) and aminophylline (250 mg), given by slow intravenous injection. Patients received each of the three treatments, on separate days, in random order using a double-blind design. Measurements were made of pulmonary function, pulse rate and blood pressure and side-effects were recorded before and at intervals up to 4 hours after drug administration. All three drugs improved pulmonary function to a significant degree and this effect was observed at 5 minutes post-treatment and lasted for 3 hours. Terbutaline and salbutamol had a significantly greater effect than aminophylline, but there was no difference between salbutamol and terbutaline. Both salbutamol and terbutaline produced tachycardia of a similar magnitude, and which returned to initial values within 90 minutes post-injection. Aminophylline did not cause tachycardia and this difference compared with the beta-agonists on pulse rate was statistically significant (p less than 0.001). Salbutamol caused a significantly greater incidence of palpitations than did either aminophylline (p less than 0.01) or terbutaline (p less than 0.05). No other differences between treatments were observed.

Adult↗
PubMedDate not supplied

Necrobiotic pulmonary nodule leading to pyopneumothorax in a case of rheumatoid arthritis--a rare clinical presentation.

A 49-year-old male patient, an active case of sero positive rheumatoid arthritis involving multiple joints with bilateral necrobiotic pulmonary nodules is presented. Initial symptoms were of progressively increasing dyspnoea. The nodule in the right lung subsequently cavitated leading to pyopneumothorax. The diagnosis of rheumatoid lung was confirmed by post-mortem.

Arthritis, Rheumatoid↗
PubMedDate not supplied

Osler-Rendu-Weber disease presenting as recurrent haemoptysis.

A young adult male with a short history of recurrent haemoptysis due to vascular malformation of right lung is presented. Lesion was not visible in the chest radiograph, nor on bronchography. CT-scan of thorax, however, showed a bunch of circinate opacities in the upper lobe of the right lung. Histopathological examination of the resected lung tissue confirmed the diagnosis.

Adult↗