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Biomedical subjects

R Jeanpierre

Publications and source records attributed to R Jeanpierre.

At least 19 recordsLinked to original sources

[Contribution of per- and trans-endoscopic pH measurements to the exploration of the upper digestive tract (author's transl)].

Per- and trans-endoscopic pH measurements in the upper digestive tract have provided new and interesting data. Performed by the authors on a series of 314 patients, they showed that the gastric pH is seldom acid, even in duodenal ulcer, and is always alkaline in gastric ulcer and gastric carcinoma. Gastritis may be divided into two groups, depending on whether the pH is normal or hypoacid (4.5 in the antrum, 2.5 in the fundus). Biopsies demonstrated the presence of intestinal metaplasia and epithelial dysplasia in 57.8% of 83 patients with hypoacid gastritis. The method therefore constitutes a simple and reliable means of determining markers of precancerous lesions.

Esophagoscopy↗

[Pancreatic injection of a tri-iodinated contrast medium. Optic and electron microscopic analysis. Experimental study in the rat].

Using the optical and electron microscope, the authors studied the effects in the rate of cathetersiation of the pancreatic ducts after laparotomy. 62 rats underwent operation, 42 of which received an injection of 30 p.cent urinary radioselectan, 10 an injection of simple isotonic saline and in 10 of which simple catheterisation without injection was carried out. With injection under high pressure, regardless of the substance used, lesions of acute pancreatitis occurred in almost all cases in the short term and in the long term lesions of localised chronic pancreatitis were fairly common. For these reasons, the authors feel that routine parenchymography is contraindicated and that only opacification of the main pancreatic ducts is permissible.

Animals↗

[Islet cell tumor with diarrhea and diabetes (glucagonoma?) associated with hyperparathyroidism. Long-term results of local-regional treatment with streptozotocin].

A case report of endocrine pancreatic tumour associated with diabetes and hyperparathyroidism is presented. Some arguments are in favour of a glucagonoma. Despite the absence of beta-cells in tumour, an exceptional result was obtained by use of Streptozotocin. This case brings up the relations between endocrine pancreatic tumours and parathyroid, and may be included in polyglandular adenoma syndrome.

Adenoma, Islet Cell↗