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Biomedical subjects

R Jury

Publications and source records attributed to R Jury.

2 recordsLinked to original sources

[Endoscopic surgery in neoplasms of Vater's ampulla].

Twenty patients with tumors located in the ampulla of Vater underwent an endoscopic papillo-sphincterectomy. Four of them were palliative procedures and 16 were curative. The patients complaints were: obstructive jaundice, pain on the right hypochondrium, digestive hemorrhage or neoplastic syndrome. The mean age was 72.6 years ranging from 54 to 87. Ten were males and 10 females. The overall mean survival was 36.2 months (S.E.+ - 5.6) ranging between 9 and 50 months. The actuarial survival 18 months after the procedure was 63.5% (S.E.+ - 13%). The survival correlated with the macroscopic shapes according to Tasaka. A comparative analysis was made between the results obtained with palliative endoscopic surgery and radical open surgery.

Aged↗

[Jaundice caused by methimazole].

Three female patients with cholestatic jaundice related to methimazole therapy are presented. The jaundice appeared after more or less 30 days of therapy. Markers for hepatitis A and B were negative in all. None of them had previous history of alcoholism or ingestion of potentially hepatotoxic drugs. Characteristically there was a marked elevation of alkaline phosphatase and gamma-glutamyltranspeptidase with only moderate increase of the aminotransferases. Liver biopsy performed in all showed intensive cholestasis with low degree of inflammatory reaction confined to the portal tracts. The three patients presented a prolonged duration of the liver injury in spite of the interruption of the drug lasting in one of them up to one year, but all ultimately resolved.

Adult↗