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Biomedical subjects

R K Bansal

Publications and source records attributed to R K Bansal.

At least 19 recordsLinked to original sources

Natural course of intraocular pressure after cataract extraction and the effect of intracameral carbachol.

Intraocular pressure (IOP) is known to increase after intracapsular cataract extraction, extracapsular cataract extraction (ECCE), and ECCE with intraocular lens (IOL) implantation. Many pharmacological agents have been used to prevent this IOP rise. We conducted a two-phase, randomized, prospective study to evaluate the natural behavior of IOP after cataract surgery and the effect of intraoperative intracameral carbachol on it. In phase 1, 102 cases were randomly assigned to three groups for recording IOP at 24, 48, or 72 hours after ECCE. The IOP at 24 (mean 20.3 mm Hg) and 48 hours (mean 22.3 mm Hg) was significantly higher than the preoperative IOP (mean 16.1 mm Hg); 26.3% of cases in group 1A (24 hours) and 44.1% of cases in group 1B (48 hours) had IOPs greater than or equal to 25 mm Hg. In phase II, intracameral carbachol (0.01%) was used in 30 cases of ECCE and in 30 cases of ECCE with IOL implantation. The IOP at 24 hours (mean 16.3 mm Hg) was not significantly higher than the preoperative IOP and only 11.6% of the cases had IOPs greater than or equal to 25 mm Hg. The mean IOP at 24 hours without carbachol was significantly higher than the mean IOP at 24 hours with it. There was no statistically significant difference between IOP in the two groups one week after surgery.

Adult

Atrial fibrillation following electrical injury.

The development of atrial fibrillation in 2 patients, following an electrical shock is reported. One patient, with an underlying pre-excitation syndrome, had to be cardioverted due to rapid ventricular rate and hypotension. The other, with normal conduction, tolerated the arrhythmia well and atrial fibrillation reverted spontaneously after 24 hours.

Adult

5-fluorouracil in trabeculectomy for patients under the age of 40 years.

In an attempt to enhance the success of trabeculectomy in patients under 40 years old, beginning 48 hours after surgery, we injected 5 to 45 mg (mean, 35 mg) of 5-fluorouracil in 10 eyes of six patients. After a mean follow up of 14.9 months (range, 6 to 27 months), intraocular pressure was below 21 mm Hg in 9 of the 10 eyes, with no antiglaucoma medication.

Adolescent

Atrophy of myelinated nerve fibers in pituitary adenoma.

A one-eyed patient was referred as a case of amblyopia secondary to myelinated retinal nerve fibers. Investigations revealed a pituitary adenoma. Following surgical ablation of the tumor, reduction in the myelination became evident. We report this rare occurrence in a case of pituitary tumor with photographic documentation for the first time.

Adenoma

Upper and lower limb standards in newborn.

One thousand live born babies of various gestational ages were studied. Using standard techniques, various limbs anthropometric measurements were taken with a non-stretchable measuring tape. Normal values and S.D. for each gestational week were calculated and their relation with gestational age statistically analysed. All these measurements correlated with gestational age. Foot length correlated best with gestational age amongst all the measurements (r = 0.9399).

Anthropometry

Blood pressure studies in Jaipur children.

A total of 1500 apparently healthy children between 1-12 years of age were examined. Blood pressure (BP) readings were taken and standard deviation and percentiles worked out for different sexes and age groups. Prevalence of hypertension was found to be 2.86% in males and 2.97% in females in 5-12 years of age group. Obesity was prevalent in 24% of the hypertensive cases. A higher value of serum cholesterol as compared to controls was also seen in the hypertensive group.

Blood Pressure

Cellular blue nevus with nevus cells in regional lymph nodes: a lesion that mimics melanoma.

We report the case of a young man who had a large, firm, nodule covered by darkly pigmented skin over the outer aspect of the right ankle and palpable right inguinal lymph nodes. The mole had enlarged rapidly during the past month, contained deeply pigmented cells with increased cellularity and mitotic activity and groups of intensely pigmented nevus cells within the marginal sinus of the inguinal nodes. The excised mass with inguinal lymphadenectomy was reported as benign cellular nevus with benign nevus cell aggregates in lymph nodes. The purpose of this report is to emphasize how cellular blue nevus can masquerade as malignant melanoma and to increase clinical awareness of this benign variant of melanocytic nevus. We have attempted to elaborate its natural history and comprehensive criteria for diagnosis, so that inappropriate surgery and chemotherapy can be avoided in this lesion which occurs conceivably often enough to be more than just a curiosity.

Adult

Occult anticonvulsant osteomalacia in North India.

Serum calcium, inorganic phosphate and alkaline phosphatase, tubular reabsorption of phosphate (TRP) estimation and radiological examination of the skeleton were conducted in 40 cases (18-50 years of age) on anticonvulsant therapy and 20 controls. The epileptic group showed a statistically significant rise in serum alkaline phosphatase and a fall in TRP. In none of the cases, however, was there clinical or radiological evidence of osteomalacia. Biochemical abnormalities were seen mainly in the youngest individuals. It seems that the critical factor for the development of anticonvulsant osteomalacia is the lack of dietary vitamin D/solar exposure or increased body requirement of the vitamin.

Adolescent

Cadaver bone as orbital implant.

Fifty-four cases of cadaver bone orbital implant are described. The results were encouraging. Cadaver bone implant is easily available and can be prepared in various sizes to fit the individual patient.

Adolescent