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Biomedical subjects

R K Bergner

Publications and source records attributed to R K Bergner.

12 recordsLinked to original sources
PubMed1985

Marked peripheral eosinophilia: a clue to allergic bronchopulmonary aspergillosis in office practice.

Allergic Bronchopulmonary Aspergillosis (ABPA) is not rare. A diagnosis of "clinically probable ABPA" should be suspected in asthmatics who are not well controlled on adequate bronchodilators, who are steroid dependent or who have recurrent pulmonary infiltrates, and who also have a positive skin test with a separate aspergillus extract. Suspicion should also stimulate pursuit of this diagnosis in asthmatics with a total eosinophil count over 500 cells/mm3 or a total serum IgE level over 1,000 IU/ml. Early detection in office practice is feasible, practical, and may be critical to avoidance of permanent pulmonary damage.

Adolescent↗
PubMed1977

Outpatient management of asthma.

Oral administration of xanthine compounds represents the first line of therapy in most patients with asthma. Establishment and maintenance of a therapeutic blood level of the medication requires regular dosgae. Oral sympathomimetic agents with predominantly beta-2 adrenergic activity, if tolerated, are often useful adjuncts to xanthine therapy. Sympathomimetic aerosols are not recommended. Cromolyn is often a valuable prophlactic agent. Corticosteroid aerosols may be useful in limiting adrenal suppression when steroids are necessary.

Adrenal Cortex Hormones↗
PubMed1975

Pulmonary hypersensitivity associated with pancreatin powder exposure.

A 25-year-old woman with obstructive, reversible pulmonary and nasal hypersensitivity apparently induced by casual, repeated inhalation of pancreatin powder (desiccated pork pancreas) is described. The powder was being employed as a dietary supplement for the patient's son, diagnosed as having cystic fibrosis. Two challenges of the diagnosed as having cystic fibrosis. Two challenges of the patient by reproducing home use of the powder resulted in repetition of a hypersensitivity symptom complex on both occasions. Vitalometry demonstrated an immediate and late response. Avoidance of pancreatin powder exposure resulted in subsidence of symptoms. Immunologic mechanisms are suggested but not proven.

Adult↗
PubMedDate not supplied

The international consensus report on diagnosis and treatment of asthma: a call to action for US practitioners.

Effective management of asthma requires accurate diagnosis and assessment of the severity of the disease. Subjective measures, such as the degree of cough, wheezing, and chest tightness, and objective assessments of pulmonary function, provide diagnostic evidence of the presence of asthma. The diagnostic criteria included in the International Consensus Report on Diagnosis and Treatment of Asthma provide one method of classifying asthma by the degree of severity. These guidelines, which were developed by the National Institutes of Health in collaboration with the International Asthma Management Project, include the US Guidelines for the Diagnosis and Management of Asthma. Only the mildest, intermittent cases of asthma generally can be managed with an inhaled short-acting beta 2-agonist given alone as needed. As the frequency or severity of the asthma increases, inhaled corticosteroids, inhaled cromolyn, or inhaled nedocromil should be added to the treatment regimen. Sustained-release theophylline, long-acting oral or inhaled beta 2-agonists, and inhaled anticholinergic agents also have a place in the treatment of selected patients.

Administration, Inhalation↗