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Biomedical subjects

R K Kuba

Publications and source records attributed to R K Kuba.

10 recordsLinked to original sources

A twin study of genetic variation in proportional radiographic alveolar bone height.

The purpose of this study was to estimate the genetic variance for alveolar bone height by means of the classic twin method and the study of monozygous twins reared apart. Panoramic radiographs were obtained from 120 pairs of adult twins (mean age = 40.4 years, S.D. = 10.4 years), for comparison of 62 pairs of monozygous twins reared together (MZT), 25 pairs of like-sexed dizygous twins reared together (DZT), and 33 pairs of monozygous twins reared apart (MZA). Mesial and distal bone heights were determined as a proportion of tooth length. A full-mouth bone score was computed for each twin by averaging these proportions from all measurable teeth. Between-pair (B) and within-pair (W) variances were computed for each twin group. The population variances (B + W) of the MZT and DZT twin groups were similar, which validated a basic assumption of the twin model. Intraclass correlations and heritability estimates were also computed for the reared-together and reared-apart twin groups. Boot-strap sampling was used to provide estimates and confidence limits for these values. The intraclass correlations for the twin groups were: MZT = 0.70, DZT = 0.52, and MZA = 0.55. The results of this study suggest that there is significant genetic variance in the population for proportional alveolar bone height.

Adolescent

An improved head-and-neck phantom for radiation dosimetry.

To obtain accurate estimates of radiation doses within the head and neck, a phantom was constructed. The osseous structures were represented by a human skull and cervical vertebrae with Mix D simulating the soft tissues originally with the bone. The soft tissues of the head and neck were also represented by this mixture of wax, plastic, magnesium oxide, and titanium dioxide with the x-ray absorption and scattering properties nearly equal to water and soft tissue. Soft tissue thicknesses and facial contours were based on depths reported in the literature and supplemented by cadaver measurements. Air passages, air cells, sinuses, and the oral cavity were left open to accurately simulate the patient. The locations of 16 anatomic sites were based on cadaver dissection and measured relationships to osseous landmarks and the skin surface. To confirm the accuracy of the phantom, doses were measured with lithium fluoride thermoluminescent dosimeters and compared with the results of other investigations reported in the literature.

Cervical Vertebrae

Radiation dosimetry in specific area radiography.

An improved head-and-neck phantom was constructed from a human skull, cervical vertebrae, and Mix D, a mixture of wax, plastic, and metal oxides with x-ray absorbing and scattering properties similar to water and soft tissues. Lithium fluoride thermoluminescent dosimeters were calibrated and then exposed within the phantom. The doses at 17 anatomic sites were calculated for each of the 18 specific area radiographs in a complete intraoral radiographic survey.

Bone Marrow