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Biomedical subjects

R K Pandhi

Publications and source records attributed to R K Pandhi.

At least 19 recordsLinked to original sources
PubMed1979

Antichlamydial antibodies in pelvic inflammatory disease.

The role of Chlamydia trachomatis in pelvic inflammatory disease (PID) diagnosed without laparoscopy was assessed by measuring antichlamydial antibodies in the patient's serum and by comparing the results with those in patients with uncomplicated non-specific genital infection (NSGI) and gonorrhoea and in non-infected controls. A modified microimmunofluorescence test was used. Patients with severe PID had significantly more positive antichlamydial IgG and IgM results than did control subjects, patients with gonorrhoea, and patients with NSGI. Less severe PID was associated with significantly raised levels of antichlamydial IgG antibodies compared with NSGI and controls and with raised levels of IgM antibodies compared with controls. Two patients with PID had lower genital tract gonorrhoea, one of whom had raised antichlamydial antibody levels. These findings may indicate a mixed infection and therapy should be reviewed in such patients. A serological diagnosis of chlamydial infection is relatively easy and cheap and enables a rapid diagnosis of chlamydial infection to be made.

Antibodies, Bacterial↗
PubMed1977

Buschke-Löwenstein's tumour presenting with urinary fistula.

A case of Buschke-Löwenstein's tumour presenting with urinary fistula is described. The large lesion in the subpreputial sac occluded the preputial opening and infiltrated beneath the skin of the shaft of the penis resulting in a fungating growth encasing the fistulous tract. The lesion responded well to 25% podophyllin, which is reportedly unusual.

Adult↗
PubMed1976

Multiple palmoplantar histiocytomas.

Four patients had multiple histiocytomas involving the palms and soles; we describe the clinical and histologic features of their disorder. Multiple lesions of histiocytoma are rare, and their occurrence on the palms or the soles has not been reported, to our knowledge. Whorled patterns of intertwining bundles of histiocytic cells and fibers were seen predominantly and most frequently on histologic examination. No recurrences were noted during a follow-up period of up to two years after removal of the lesions. They appear to be distinct from juvenile fibromatoses and eruptive histiocytomas.

Adult↗
PubMed1975

The effects of some hair oils and unsaturated fatty acids on experimentally induced dermatophytosis.

Antimycotic effect of mustard and coconut oils, oleic and palmitic acids on experimentally produced dermatophytic infection on hairy skin in the guinea pigs was studied. Mean Duration of Infection (MDI) was significantly reduced in all experiments where coconut and mustard oils or unsaturated fatty acid (oleic acid) were used. The significance of these results in realtion to Tinea capitis in humans is discussed.

Animals↗
PubMed1975

A study of the immunological status of patients with dermatophytoses.

22 patients with Trichophyton rubrum infection were studied for some of their immunological parameters. The trichophytin skin test performed with commercially available Dermatophytin (Hollister-Stier) gave immediate positive reaction in 3 patients. All the other patients gave negative delayed and retarded reactions. In vitro response to PHA of the peripheral lymphocytes was significantly depressed in patients compared to the controls. No relationship could, however, be established between the severity, duration or extent of the disease and the depression of the lymphocyte response. IgG and IfA were found to be within normal limits. IgM levels were significantly depressed which was probably artefactual in nature.

Humans↗