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Biomedical subjects

R K Ranga

Publications and source records attributed to R K Ranga.

3 recordsLinked to original sources

Nasal mucociliary clearance in healthy children in a tropical country.

INTRODUCTION: Nasal mucociliary clearance is an important physiological function of nasal cavity that helps in protecting the lower respiratory tract from undesirable organic and inorganic matter including the micro organisms. The study was designed to establish normal mucociliary clearance time in healthy children in a tropical environment. MATERIAL AND METHODS: The study was carried out in 100 randomly selected normal school children aged 4--15 years using saccharin method. The diseases that are known to affect the nasal mucociliary clearance were excluded. The study variables were age and sex. RESULTS: Mean nasal mucociliary clearance time was 5.7+/-2.59 min with no significant difference between males and females. The clearance time was found to be impaired in groups A and B including children of 4--7 and 8--11 years of age respectively. CONCLUSION: Nasal mucociliary clearance is impaired in children of either sex between 4 and 11 years probably due to subclinical adenoiditis. However clearance returns to normal level at the time of puberty, which coincides with adenoids involution.

Adolescent↗

Multiple papilloma larynx.

Multiple papilloma of larynx is caused by human papilloma virus. We treated sixteen such cases (10 males and six females) in the last 10 years. All presented with hoarseness while six presented with difficulty in respiration. Three patients needed tracheostomy, all had difficult decanulation, and one developed laryngotracheal stenosis and could not be decanulated. All were treated by surgical excision; ten had recurrence. Four patients were treated with post operative Acyclovir with no recurrence in three cases.

Acyclovir↗

Nasal mucociliary clearance in adenotonsillar hypertrophy.

The nasal mucociliary clearance time was studied using Andersen saccharin method in 50 normal children and 50 age and sex matched patients of adenotonsillar hypertrophy, which was repeated one month after adenotonsillectomy. The normal mucociliary clearance time in healthy children was found to be 8.55 +/- 2.11 minutes. A significant impairment in nasal mucociliary clearance time was noted in children suffering with adenotonsillar hypertrophy which was 16.97 +/- 3.1 minutes, and early adenotonsillectomy restored the mucociliary clearance to a normal 8.7 +/- 2.14 minutes.

Adenoidectomy↗