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Biomedical subjects

R Kamiyama

Publications and source records attributed to R Kamiyama.

At least 73 records · Page 4Linked to original sources
PubMed1985

[Comparison of three pathologic classifications (Rappaport, LSG and Working Formulation) for the treatment of non-Hodgkin's lymphoma].

Comparison of three pathologic classifications (Rappaport, LSG and Working Formulation) was made for 292 cases of non-Hodgkin's lymphoma who were treated at the Department of Radiology, Tokyo Medical and Dental University, from 1952 to 1984. The Working Formulation was found to be the most convenient classification for the treatment of non-Hodgkin's lymphoma in Japan. There were two remarkable characteristics in the cases of non-Hodgkin's lymphoma classified by the Working Formulation. They were better case distribution having a strong relation to clinical prognosis and fewer high-grade cases in Waldeyer's ring lymphoma.

Adolescent↗
PubMed1984

Gastric plasmacytoma and multisystem autoimmune disease.

A 54-year-old women with solitary gastric plasmacytoma, Ig M and kappa-light chain type, associated with multisystem autoimmune disease is described. The gastric plasmacytoma developed seven years after the diagnosis of Hashimoto's thyroiditis, primary biliary cirrhosis and Sjögren's syndrome. We speculate that this plasmacytoma developed in association with an immunodeficient and/or immunosuppressed state resulting from multisystem autoimmune disease and therapy.

Autoimmune Diseases↗
PubMed1984

[HCG-positive cells in seminoma of the testis].

In a retrospective study of 38 patients with pure seminoma, serum and urine levels of human chorionic gonadotropin (HCG) were measured and the cellular origin of HCG-like substance was searched using the technique of indirect immunoperoxidase on step sections of the tumors. Eight of the patients had elevated HCG in serum or urine, and 5 had HCG-positive cells in the sections of tumor specimens. With this technique, two types of HCG-positive cells were identified, syncytiotrophoblastic giant cells (STGC) and mononuclear cells otherwise indistinguishable from seminoma cells. Patients in the present series responded well to conventional radiation therapy or cytotoxic chemotherapy and had a favorable outcome regardless of the presence of STGC or slightly elevated HCG levels.

Adult↗
PubMed1983

Emperipolesis and annulate lamellae in erythroleukaemia.

The bone marrow in the erythraemic phase of 2 erythroleukaemia patients was studied electron microscopically. Emperipolesis of erythrocytes as well as annulate lamellae were revealed in the cytoplasm of the erythroblasts of these cases. It is assumed that these findings show a high rate of erythroblastic proliferation. This is the first report of emperipolesis within the erythroblast by erythroleukaemia. In addition, other various abnormalities, namely, nuclear-cytoplasmic asynchrony, nuclear bleb or cleft formation, abundant glycogen particles and ferruginous micelles in mitochondria such as described in some previous reports, were also recognized.

Adult↗
PubMed1983

[Liver cell carcinoma with extensive proliferation of sarcoma-like neoplastic cells--an autopsy case].

A 73-year-old male was admitted with suspected Grawitz tumor. Aspiration cytology from the tumor was diagnosed as Class V with suspected sarcoma. He died 17 days after admission. Autopsy revealed this to be a massive hepatic tumor occupying over half of the right lobe. It showed protrusion into the right retroperitoneum. Histology of the tumor evidenced widespread proliferation of sarcoma-like neoplastic cells besides a minute area of definite liver cell carcinoma in the center of the tumor mass. Definite transitional features between liver cell carcinoma and a sarcomatous pattern, the latter involving a major part of this tumor, were noted. Thus, we diagnosed this tumor to be liver cell carcinoma with a sarcoma-like histological pattern. The possibility of collision tumor or carcinosarcoma could be ruled out.

Aged↗
PubMed1983

[Histopathological evaluation of minute stomach cancer].

We histologically examined 17 lesions from minute gastric cancer (less than 5 mm in diameter). Flat or IIb type was frequently seen in minute cancer (47%); the depressed type was predominant in ordinary early gastric cancer (72%). Differentiated adenocarcinoma was noted more often in minute cancer (88%) than in ordinary early gastric cancer (61%) or advanced cancer (45%). Differentiated type minute cancer was frequently associated with severe atrophic gastritis (93%) and intestinal metaplasia (73%). There was no evidence for the preexistence of chronic peptic ulcer, because no fibrosis was present in the gastric wall beneath the minute cancerous lesions.

Adenocarcinoma↗
PubMed1983

[Autopsy case of atypical medulloblastoma in an adult].

A 24-year-old female complained of headache and vomiting. The brain-CT scan demonstrated a tumor shadow in the right cerebellar hemisphere. The tumor was partially resected, and irradiation therapy was started. She died of intraventricular hemorrhage about 6 months after the onset of symptoms. Autopsy revealed a recurrent tumor mass in the cerebellum extending to the brain stem. It showed systemic metastases to the leptomeninx, liver, bones and ovaries. Histological examination showed a tumor which was a primarily composed of typical medulloblastoma cells with occasional Homer-Wright type rosettes. It partly showed glioblastoma-like configuration. Some tumor cells were positive for GFAP by the PAP method, suggesting glial differentiation.

Adult↗
PubMed1982

A scanning electron microscopic study of the boundary zone of the human spleen.

The structural characteristics and cellular elements of the boundary zone between the white and red pulp of the human spleen were studied by SEM and TEM. The boundary zone consisted of both the perifollicular region and the region surrounding the periarterial lymphoid sheath. The perifollicular region was further subdivided into two, equally thick layers. The inner half layer of the perifollicular region outside the mantle zone of the lymph follicle was composed of tightly packed medium-sized lymphocytes, interspersed by a small number of reticular cells. The outer half layer was composed of a reticular cell meshwork containing blood cells in vessels, which communicated with the splenic cords of the red pulp. Intermittent rows of reticular cells distinguished the outer from the inner half layer. The region surrounding the periarterial lymphoid sheath revealed the same type of reticular cell meshwork as the outer half layer of the perifollicular region. Capillary ends opened into the reticular cell meshwork, which suggested the presence of an open circulation in the human spleen. A deep lymphatic vessel which communicated with the periarterial lymphoid sheath was noted.

Female↗
PubMed1982

Fibrous long spacing-like fibers in the bone marrow of myloproliferative disorder.

Bone marrow obtained at autopsy from four cases of primary myelofibrosis and four cases of chronic myelogenous leukemia, was studied electron microscopically. In all the cases of primary myelofibrosis, the excess of collagen fibers in the bone marrow showed mostly about 2,000 A diameter and 1,000 A periodicity, i.e. fibrous long spacing (FLS)-like fibers. These FLS-like fibers were also seen in secondary myelofibrosis in three of the four cases of chronic myelogenous leukemia. These fibers were abundant around fibroblasts and small blood vessels. An apparent continuity between the dark bands of FLS-like fibers and the basement membrane material around small blood vessels was also revealed. Moreover, it was observed that these dark bands of FLS-like fibers contained acid mucopolysaccharides.

Adult↗
PubMed1982

Mucoepidermoid carcinoma of the thymic region.

A case of mucoepidermoid carcinoma in thymus in a 59-year-old Japanese female is presented. She died of cardiac tamponade due to tumor invasion ater a 5 years' clinical course. At autopsy the main tumor was found in the thymic region with metastases to the sternum, regional lymph nodes, pericardial, and left pleural cavity. The mucoepidermoid carcinoma might be probably originated from a hen's egg-sized cyst which was located in the upper posterior aspect of the tumor-involved thymus. No teratomatous components were present. The cyst was most likely to be of thymic or bronchogenic cyst origin, though it was not determined, in view of the lining with pseudostratified ciliated columnar epithelium of the cystic wall and the surrounding with the thymic tissue outside. Moreover, there was thymic hyperplasia with germinal center that was compatible with SLE-like symptoms in her past history and autoimmune nature of the autopsy findings of pulmonary fibrosis.

Carcinoma↗
PubMed1982

Carcinomas of the esophagus with synchronous or metachronous primary carcinoma in other organs.

Twenty-eight patients with esophageal carcinoma and one or more separate primary carcinomas in other organs were treated from 1960 to 1980, representing 8.3 per cent of the 339 cases of esophageal carcinoma observed during this period. The most frequent sites of the additional tumors were the oral cavity and pharynx (11 patients) and the stomach (12 patients). Awareness of the frequent combination of esophageal carcinoma with other primary neoplasms in the sites mentioned may lead to the detection of small curable malignant tumors.

Aged↗