Biomedical subjects
Publications and source records attributed to R Kirchhoff.
In liability cases caused by accidents, the actual compensation for consecutive sustained damage to the patients' health and pain is not sufficient. Moreover, besides payments for a loss of earning capacity, the compensation for loss of efficiency in daily life such as for domestic work might be necessary. Therefore, distinct indications for the expert's appraisal exist.
We describe a way of achieving immediate painfree mobilisation after tenolysis or tenosynovectomy in Zone II. Bupivacaine is instilled along the flexor tendon sheath through a thin percutaneous catheter with an antibacterial filter.
Explore the source record for details and available documents.
A 48-year-old man had type IIb hyperlipoproteinaemia which could not be satisfactorily treated with diet alone (total cholesterol 351 mg/dl, HDL cholesterol 36 mg/dl, triglycerides 480 mg/dl). Treatment with lovastatin (an HMG-CoA reductase inhibitor) was then started at a dosage of 20 mg daily. After two months on the drug cholestatic jaundice developed (total bilirubin 6.15 mg/dl). The jaundice and abnormal biochemical findings regressed within two weeks of discontinuing lovastatin. All other possible causes of jaundice were excluded. These observations indicate that, in addition to hepatocellular damage, lovastatin may in rare instances also exert a cholestatic effect.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
A new preservation system is described. In this unit 17 dog kidneys were nonpulsatile perfused with hypothermic human albumin for 72 hrs and then transplanted. All kidneys started immediately to function and the PAH and inulin clearances attained normal values at least at the 7th postoperative day. The quality of the immediate function is referred to the applied perfusion pressure (20 mm Hg) and the applied temperature of the perfusion medium (7.5 degrees C). During preservation substrate utilization (oxygen, unesterified fatty acids) and the accumulation of toxic metabolic products (ammonia, uric acid) were controlled in the perfusate. Their importance concerning to the limitation of preservation time is discussed.
Thirty-six dog kidneys were perfused with different perfusion pressures (between 15 and 60 mm. Hg) for 72 hours and then transplanted. Hypothermic human albumin was the perfusion fluid. Enzyme release, kidney weight, and renal oxygen consumption were measured during perfusion. Kidneys perfused with a flow rate of 0.8 ml. per gram per minute (21 mm. Hg mean perfusion pressure) showed the smallest increase in kidney weight and the best function after transplantation. Renal vascular resistance was independent of the level of the perfusion pressure and renal oxygen consumption was independent of the applied flow rate. It is concluded that the perfusion pressure applied with hypothermic perfusion should be as low as possible because in this way kidney damage caused by perfusion can be avoided most easily.
36 dog kidneys were perfused with different perfusion pressures (between 15 and 60 mm Hg) for 72 hrs and then transplanted. Hypothermic human albumin was the perfusion fluid. Kidneys perfused with a flow rate of 0.8 ml/g/min (21 mm Hg mean perfusion pressure) showed the smallest increase in kidney weight and the best function after transplantation. Renal vascular resistance was independent of the level of the perfusion pressure and renal oxygen consumption was independent of the applied flow rate.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.