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Biomedical subjects

R Knight

Publications and source records attributed to R Knight.

At least 55 records · Page 3Linked to original sources

Mortality in relation to the functional capacities of people with disabilities living at home.

The mortality experienced by a group of 1534 impaired people identified by means of a census-type survey of all households in the City of Canterbury is related to the degree of difficulty in carrying out selected self-care activities as reported by the impaired people. Although not entirely consistent, the findings in relation to people in their own homes agree with previously reported findings among patients in long-stay hospitals and residents in institutions that increasing difficulties in self-care (and therefore of dependency) are associated with increased mortality rates. These findings suggest that there is no clear boundary between some services for disabled people and those for terminal care, and that many severely handicapped people at home require co-ordinated and flexible care from nurses, social workers, and doctors.

Activities of Daily Living

Long-term results after surgical correction of Ebstein's anomaly: report of two cases.

Two patients with Ebstein's anomaly had valve replacement with Starr-Edwards cloth-covered valves 11 and 8 years ago. They have been asymptomatic and very active despite the absence of anticoagulation. These cases provide some of the long-term results needed for proper evaluation of the different methods of operative treatment of Ebstein's anomaly.

Adolescent

Enflurane anesthesia and changes of intracranial pressure.

Enflurane has been recommended by some as an ideal agent for use in neuroanesthesia. There is no statistically significant alteration of normal intracranial pressure with enflurane anesthesia. However, supporting a clinical impression, this study demonstrates in dogs that enflurane will significantly increase an already elevated intracranial pressure.

Animals

The use of Ferastral in iron-deficient, non-pregnant Gambian adults.

A new parenteral iron preparation, iron-poly (sorbitol-gluconic acid) complex, (Ferastral) has been evaluated in the treatment of iron-deficient, non-pregnant Gambian adults. A total of twenty patients of both sexes were included in the study. The cause of anaemia in the majority of cases was hookworm infection but also other diagnostic categories were present. Sixteen patients completed their treatment without difficulty. All patients showed a good initial haematological response. Over the first three weeks the mean daily increments followed a linear trend. There was a significant inverse correlation between initial haemoglobin concentration and the increment in concentration after three weeks treatment. Side-effects were noted in four patients; in two patients it was ascribed to treatment, in two there was concurrent infection. Parenteral iron therapy is considered to have definite advantages over oral iron in the tropics because of certainty of administration, replenishment of iron stores, and effectiveness when small bowel disease or dietary factors reduce absorption.

Adolescent