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R Kokles

Publications and source records attributed to R Kokles.

At least 19 recordsLinked to original sources
PubMed1990

[Enzymatic protein hydrolysate as the N-source for cell culture].

Supplement T, a preparation for cell culture growth, is just as effective as commercially available tryptose. It has met high demands throughout its application over six years under conditions of large-scale production of permanent cell lines. Supplement B has been used with good success in commercial production for breeding of FMD virus in BHC cells of IBR/IPN and PI-3 viruses in calf kidney cells cultures and of embryonic duck fibroblast cell cultures for production of vaccines against Marek's disease.

Animals↗
PubMed1975

[Isolation of reoviruses from mink].

In this first report of the isolation of reovirus from mink, isolates were obtained from 18 to 26 young mink with viral enteritis, by using cultures of cat kidney cells. The isolated also produced cytopathic changes in cell cultures of mink kidney, dog kidney, piglet kidney, calf kidney, bovine embryonic kidney and calf testis. A characteristic feature was the formation of eosinophilic inclusion bodies in the cytoplasma of culture cells. Haemagglutination tests were negative with erythrocytes from cat, rabbit, pig, horse and cattle. Attempts to infect old and young mink, kittens and ferrets with tissue culture material failed. It was not known to what extent this second infection with reovirus influenced the course of mink viral enteritis.

Animals↗