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Biomedical subjects

R Król

Publications and source records attributed to R Król.

At least 37 records · Page 2Linked to original sources
PubMed1992

[Biomechanical aspects of surgical treatment of secondary stenosis of the spinal canal in the lumbosacral region].

In experimental studies and on clinical material, behaviour was checked of intervertebral discs and vertebrae under the axial pressure: which is the being exerted by the trunk weight, as well as the behaviour of the adjacent mobile segments after "diskoplasty" operation or vertebral interbody stiffening. The material pertaining to the experimental part comprises 6 undamaged spine preparations of the lumbosacral segment, while the clinical part consists of 60 patients out of 143 subjects having been operated on by "diskoplasty" or vertebral interbody stiffening from the approach through fenestration, hemilaminectomy, or plastic laminectomy. The results of performed experimental studies and spodylometric analysis of radiograms in patients treated operatively by decompressing the vertebral canal and by "diskoplastic" stabilization of the vertebrae, or vertebral interbody stiffening permit the following observations. The most favourable localization of the transplant is the medial and posterior parts of the vertebral interbody space, since in both segments L4/L5 and L3/L4 it reproduces the height of the vertebral interbody space, the height and width of intervertebral foramen, widens the intervertebral foraminis, and reduces the lumbar lordosis, which advantageously changes the biomechanic relations, transferring loads of the posterior to the anterior vertebral column. The localization of the transplant in the anterior part of the vertebral interbody space, in fact, increases the anterior vertebral interbody space, but decreases the height of posterior interbody space, the vertebral interbody angle alpha as well as the height and width of the intervertebral foramen. The retroshifting of vertebral L4 indicates mobile segment instability. By implementing a transplant of matching height and appropriate localization in vertebral interbody space, it is possible to increase or reduce the angle between the vertebral bodies at the operative level, widening the vertebral interbody space in anterior and posterior parts. The localization of the bony transplant in the anterior part of vertebral interbody space, involving the clinical material, caused in 65% constriction of intervertebral foraminis, retroshifting of vertebrae L4 and L3, and recurrence of algesic complaints, which may be elucidated by instability of the operated on or adjacent mobile segments.

Adult↗
PubMed1992

[Treatment of the deformities associated with hypoplasia or agenesis of the sacral bone].

On the basis of follow-up of 5 children treated because of the deformities associated with sacral agenesis or hypoplasia as well as on the literature the authors came to the conclusion that congenital dislocation of the hip, clubfoot and flatfoot are the most common. The aim of the treatment is to prepare the child for walking before the end of the first year of life. Since the deformities mentioned are resistant to conservative treatment they require a very sophisticated surgery with the constant adjustment of the operating plan in every stage of the management. The type of hip surgery should be selected individually.

Abnormalities, Multiple↗
PubMed1992

[A case of sacral agenesis coexisting with Goldenhar syndrome].

A case of two coexisting embryopathies has been described. The deformities within the sacral bone and systemic anomalies led to the diagnosis of sacral agenesis; Goldenhar syndrome has been differentiated with other disturbances of branchial arches formation.

Abnormalities, Multiple↗
PubMed1992

[Mechanical properties of tissue generated as a result of fascia lata grafted into an articular cartilage defect of the knee joint (experimental observations)].

In 64 sheep knees crushing strength and elastic recovery of the tissue generated on the basis of fascia lata grafted into articular cartilage defect in the knee after active motion and load has been assessed. The newly generated tissue is characterized by increasing in time thickness, deformability and elastic recovery the greater the deeper the defect was. Primarily, the new tissue is able to carry smaller loads but after 26 weeks is capable of carrying much greater loads then the cartilage; it has also better plastic and elastic properties.

Animals↗
PubMed1992

[Treatment of funnel chest by a modified Brown method].

A series of 19 patients operated on because of pectus excavatum has been analyzed to assess results of Zuk modification of the Brown method. Vital lung capacity, funnel volume, physical fitness, and cosmetic result have been assessed. An asymmetry and developmental disturbances within insertions of pectoralis major, rectus and oblique abdominal muscles were found as well as developmental disturbances of costal cartilage. In 95% of cases a positive patient opinion along with satisfactory functional and cosmetic result have been achieved.

Adolescent↗
PubMed1992

[Long-term results of knee joint rehabilitation after fascia interposition].

The method, schedule and results of rehabilitation in patients with the chondral defects in knee joints treated by partial or total fascial grafting were presented. In the series of 114 patients followed up from 1 to 19 years after operation there were 56.1% good and fair results in the group with partial grafting and 26.6% in the group with total fascial grafting. An aggravation of rheumatoid process, coincidence of deformities in adjacent joints, weakening of muscles and ligaments in the knee and Hoffa pad grafting during the development of the method yielded 17.7% bad or unsatisfactory results.

Adult↗
PubMed1991

[Morphological evaluation of fascia lata tissue implantation for chondral defects in the knee joint of sheep under active motion and load].

Experiments carried out on 64 knees of 32 Lein sheep with superficial and deep chondral defects of the patella and femoral condyles covered by autogenic fascia lata grafts indicate that under active motion and load the grafted tissue after 6 weeks is thinner, fragile and lustreless. Quantitative and qualitative deterioration of collagen fibers, almost complete atrophy of elastic fibers and increase in number of cells and vessels is observed under microscope. After 9 weeks remodeling of the fascia occurs which thickens and increases in number of fascicular collagen fibres, after 12 weeks the foci of neochondrogenesis can be found. After 26 weeks a new hyaline like cartilage is generated surrounded by connective tissue containing fascicular collagen and elastic fibers. At this point remodeling is not yet completed.

Animals↗
PubMed1989

[Contemporary methods of imaging injuries of the spine and spinal cord].

A review of current methods of visualization of injuries of the axial organ on the basis of the literature from the last decade, including also the author's own experience, has been done. The techniques of visualization accessible in Poland have been discussed more widely.

Diagnostic Imaging↗
PubMed1989

[Treatment of dysfunction of the knee joint in rheumatoid arthritis by fascial interposition].

A surgical treatment method consisting in sewing on of the fascia lata on the cartilageless, loaded and needing painless sliding parts of the joint has been presented. In order to transform the fascia into the painless fibrous cartilage, it is necessary to begin early postoperative rehabilitation as soon as at 4-7 days after operation and continue until maximal function and efficiency of the knee is achieved. The follow-up was up to 4 years and full function was found in 11 patients, improvement after partial patients, and no improvement in 6 patients. Better results were obtained after partial rather than total interposition. Poor results were found in the patients with great contracture and muscular atrophy before operation and with difficulties in rehabilitation caused by other joints. Thus, interpositions is contraindicated in late age, great deformations and difficulties in rehabilitation. This method may fill the empty place in the treatment methods between synovectomy and alloplasty of the knee.

Adult↗
PubMed1983

QT interval prolongation and increased plasma catecholamine levels in patients with mitral valve prolapse.

The heart rate corrected QT interval (QTc) and plasma catecholamine (CA) and norepinephrine (NE) levels were measured in 15 symptomatic patients with idiopathic mitral valve prolapse (MVP) and in 19 control subjects. MVP patients showed longer mean QTc and were divided into two groups: group A normal QTc (greater than 440 msec) and group B prolonged QTc (less than 440 msec). In supine resting conditions CA levels were as follows: group A 0.420 +/- 0.035 ng/ml and group B 0.619 +/- 0.104 ng/ml (p less than 0.05); both were greater than control values (0.348 +/- 0.017 ng/ml, p less than 0.005). NE levels were as follows: group A 0.350 +/- 0.031 ng/ml and group B 0.376 +/- 0.052 ng/ml (NS); both were greater than control values (0.242 +/- 0.025 ng/ml, (p less than 0.05). When a standing position was assumed, CA and NE levels increased significantly in all groups but this was most marked in group B as compared to control levels (CA: 1.039 +/- 0.123 ng/ml versus 0.625 +/- 0.037 ng/ml; NE: 0.737 +/- 0.076 ng/ml versus 0.504 +/- 0.031 ng/ml) (p less than 0.001 and p less than 0.05, respectively). Thus the longest QTc was observed in patients with MVP who had the highest levels of CA and NE, in both supine and standing positions. These data may account, in part, for the occurrence of severe ventricular arrhythmias in some patients with MVP and may offer a rationale for adrenergic blockade in that subset of patients with MVP and markedly prolonged QTc.

Adrenergic beta-Antagonists↗
PubMed1980

Hypertrophic cardiomyopathy in Friedreich's ataxia: symmetric or asymmetric?

We evaluated 15 patients with Friedreich's ataxia (FA) to define the incidence of myocardial involvement and the type of cardiomyopathy observed. All patients with FA had either ECG, vectocardiographic or echocardiographic abnormalities, suggesting some degree of myocardial involvement. In contrast to reports indicating that asymmetric septal hypertrophy (ASH), often obstructive, is associated with FA, symmetric, concentric hypertrophic cardiomyopathy (SCH) was the predominant abnormality (sixty-seven percent of patients). Echocardiograms should be performed periodically in all FA patients since this technique allows the detection of cardiac hypertrophy.

Adolescent↗
PubMed1980

Influence of methionine-enkephalin and morphine on myoelectric activity of small bowel.

Enkephalins, naturally occurring peptides with powerful opiatelike effects, have recently been detected throughout the tissues of the alimentary tract, but their role is unknown. This study was designed to compare the effects of methionine-enkephalin (met-enkephalin) and morphine on the myoelectrical pattern of the small bowel. Five conscious dogs were prepared with electrodes spaced 25 cm apart along the entire small intestine. Spike activity and slow waves were recorded with a Beckman Dynograph. Records were obtained in fasted conditions and following a meat meal or intravenous infusion of caerulein while animals received intravenous infusion of either met-enkephalin or morphine in various doses (range 10-160 microgram/kg . h). Met-enkephalin at a dose of 40 microgram/kg . h caused a significant decrease in spike activity and in the frequency of bursts of the interdigestive myoelectric complexes (IMC), whereas morphine almost doubled the frequency of the IMC. Met-enkephalin in dogs given food or infused with caerulein significantly decreased the fed-type spike activity of the small bowel, whereas morphine did not affect it. The effects of met-enkephalin and morphine on the intestinal myoelectrical pattern can be reversed by naloxone, an opioid antagonist, suggesting that they are mediated by separate opioid receptors.

Action Potentials↗