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Biomedical subjects

R Krakauer

Publications and source records attributed to R Krakauer.

At least 19 recordsLinked to original sources
PubMed1990

[Urinary symptoms in elderly women in nursing homes. Frequency and social consequences of urinary incontinence in elderly women living in nursing homes].

All 278 female residents of nursing homes in the County of Roskilde were assessed as regards the extent and severity of urinary incontinence and possible urinary infections. A total of 168 (58.5%) were incontinent. Culture of the urine was performed in 210 women and significant bacteriuria was demonstrated in 50%. Thirty-four out of the total of 287 women (12%) had indwelling catheters. In incontinent women without catheters, great quantities of urine were often voided involuntarily. Despite this, only few were subjectively inconvenienced or inhibited in their social activities. The investigation revealed a connection between urinary incontinence and reduced mobility while no connection was observed with current urinary infections, intake of medicaments and parity. It is emphasized that these results are based on findings in very old women living in nursing homes.

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PubMed1981

Relative reference values for clinical chemical and haematological quantities in 'healthy' elderly people.

A search of the literature revealed a paucity of data on reference values for clinical chemical and haematological quantities in reasonably 'healthy' ambulant persons above 65 years of age. On the basis of 90 papers, concerning 37 different types of quantities, the median values for men and for women at 30, 50, 65, and 80 years are calculated relative to the value in men at 30 years. This transformation reduces influences of analytical and demographic factors that have caused considerable systematic differences in the original data. The reference distribution is described as regards symmetry and the change in dispersion with age. The results are given in a table and show four types of changes with age: no significant variation, a fall, an increase or a maximum somewhere between 30 and 80 years; the type of change often depends on sex.

Adult↗
PubMed1980

Prevalence of skin diseases in old age.

The prevalence of skin disorders was studied in an elderly population comprising 584 individuals. The mean age was 80 years (range 55-106). The prevalence of pityriasis of the scalp and asteatosis was high, 44.3% and 28.9%, respectively. Psoriasis vulgaris was found in 2.9%, vitiligo in 1.2%, and contact dermatitis in 3.8% of the group.

Aged↗
PubMed1978

Digoxin concentration in choroid plexus, brain, and myocardium in old age.

Thirteen aged persons receiving digoxin until the time of death were examined by autopsy, and digoxin concentrations were determined in samples from various tissues (the choroid plexus, grey and white brain matter, left and right ventricular and left and atrial myocardium, diaphragm, and musculus psoas major). These concentrations were related to the digoxin dose and duration of treatment. No significant difference was found between the concentration of digoxin in the choroid plexus and left ventricular myocardium, whereas there were significantly lower concentrations in the right ventricular myocardium and still lower concentrations in the other tissues analyzed. Independent of the digoxin dose, the digoxin concentrations in the choroid plexus tended to be lower in persons treated for a short time before death than in those treated for longer periods of time. Similar differences were not observed in the other tissues, suggesting a slower rate of digoxin uptake in the chroid plexus compared with the myocardium and other tissues. The implications of these findings for the effects of digoxin treatment on the production of cerebrospinal fluid are discussed.

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PubMed1978

Oral zinc therapy in geriatric patients with selected skin manifestations and a low plasma zinc level.

A geriatric population comprising 585 inhabitants of an institution for the aged was studied. Twenty-six persons with a mean age of 82 years were selected because of skin manifestations suggestive of chronic zinc deficiency. In 10 of the patients a subnormal plasma zinc level was found. This hypozincaemic group underwent a 4 week trial with zinc sulphate tablets, 0.6 g daily. The therapy failed to alleviate the skin condition in any of the patients, thus indicating that the changes were not caused by zinc deficiency. In the hypozincaemic group, plasma albumin was subnormal in all patients and significantly lower than in the normozincaemic subjects. The correlation between plasma zinc and plasma albumin levels in all 34 patients studied was highly significant (rs = 0.69, p less than 0.001). As plasma albumin tends to fall to subnormal concentrations with age, this explains why plasma zinc may be low in the elderly without indicating a state of zinc deficiency. After 2 and 4 weeks' zinc therapy, the mean plasma zinc concentration of the hypozincaemic group rose significantly from 9.5 to 17.6 and 23.4 mumol/1. This increase is higher than the rise observed in younger patients receiving an identical zinc sulphate dosage.

Aged↗