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Biomedical subjects

R Krapf

Publications and source records attributed to R Krapf.

80 records · Page 5Linked to original sources
PubMed1985

[Potassium regulation--current understanding from a clinical viewpoint].

Mechanisms of renal potassium excretion and internal potassium balance as the main determinants of serum and/or total body potassium are discussed. Renal handling of potassium is reviewed, with particular attention to the effects of diuretics, acid-base disturbances and aldosterone-deficient states. Among the regulatory processes of internal potassium balance, the importance of adrenergic stimuli/drugs, of acid-base balance, and of magnesium and insulin is stressed. Physiologic and pathophysiologic evidence provides the basis for discussion of relevant clinical implications.

Acid-Base Equilibrium↗
PubMed1985

[Can carboxyhemoglobin determination be performed in family practice?].

Carboxyhemoglobin concentrations were measured in venous (EDTA) blood samples from 16 cigarette smokers. The determinations were carried out up to 72 hours after venipuncture in blood stored at 20 degrees C and 37 degrees C and after hemolysis and storage at 20 degrees C. No special precautions to avoid exposure of the samples to room air were taken. Comparison of these determinations with an "ideal" reference value (immediate determination, no O2 access) indicates that changes in COHb concentrations are minimal for the first 48 hours (range of mean concentration changes: -0.28% COHb to +0.19% COHb). It is concluded that COHb determinations in venous blood samples yield reliable results for practical diagnostic purposes, even without time-consuming and costly conservation procedures.

Blood Preservation↗
PubMed1985

[Echocardiography detection of intracavitary ventricular tumors].

Intracavitary ventricular tumors were found in 3 male patients (newborn, and 18 and 23 years old) by 2-D echocardiography (metastasis of an osteogenic sarcoma in the right ventricle, teratoma embryonale growing from the retroperitoneum into the right ventricle, rhabdomyoma of the left ventricle). They all showed a uniform echo pattern and two of them were pedunculated. Wall motility, valves and cardiac dimensions were normal. In each case diagnosis was confirmed intraoperatively or at autopsy. Clinically the metastasis of the osteogenic sarcoma presented as obstruction of the superior vena cava, whereas the teratoma embryonale imitated tricuspid valve disease. The rhabdomyoma caused a systolic murmur and severe postpartal sinus bradycardia. It was successfully removed on the basis of echocardiography alone. 2-D echocardiography is a reliable, noninvasive diagnostic tool for evaluation of intracavitary, ventricular tumors.

Adolescent↗
PubMed1981

[Acute exposure to CS tear gas and clinical studies].

A case of serious intoxication with CS tear gas (o-chlorobenzylidene-malononitrile) is reported in a previously healthy male subject of 43 years involving pulmonary edema complicated by pneumonia, signs of heart failure and evidence of hepatocellular damage. Comparison with animal and human exposures supports the etiologic and pathogenetic role of CS tear gas in the present case. The pulmonary edema may have been the consequence of unusual conditions of exposure and/or increased individual susceptibility. The question of the "safety" of CS tear gas is discussed.

Adult↗
PubMed1981

A fatality during haloperidol treatment: mechanism of sudden death.

The authors report a case of unexpected sudden death in a woman receiving relatively high dose of haloperidol. They postulate that drug-induced laryngeal spasm leading to cardiac arrest via vagal reflexes may represent the mechanism of neuroleptic sudden death in some cases.

Adult↗
PubMed1981

Lethal vasculitis of coronary arteries in a neonate and two infants: possible neonatal variant of the MLNS/IPN complex?

An unusual case of fatal myocardial infarction in a neonate due to coronary arteries is compared with two lethal cases of Mucocutaneous Lymph Node Syndrome and/or Infantile Periarteritis Nodosa (MLNS/IPN). The neonatal coronary arteritis was pathologically indistinguishable from typical forms of MLNS/IPN, which cannot be reliably separated and whose strange epidemiologic features as well as their etiology(-ies) remain to be clarified. It is suggested that further research of the etiology of MLNS/IPN should be aware of a possible neonatal variant of this syndrome.

Arteritis↗