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Biomedical subjects

R Kubát

Publications and source records attributed to R Kubát.

At least 19 recordsLinked to original sources

[Incidence of HBs-antigen in diabetics. III. Results of examination after 5 years].

By examination of a group of 617 diabetics treated by oral antidiabetics (PAD) and 263 treated with insulin for HBs-antigen carriership (HBsAg) by counter immunoelectrophoresis (CIEP) a total of 34 HBsAg carriers were detected (3.84%). This number comprised 9 treated with PAD (1.5%) and 25 insulin-treated ones (9.5%). Only six were younger than 60 years, the remaining 28 were older. Comparison with results assembled in 1984 revealed that in both groups during the five-year interval a marked decline of the prevalence of carriership had occurred--in the PAD treated group from 4.9% to 1.5% and in the insulin treated group from 29.1% to 9.5%. The decline is above all due to the high mortality of diabetics who are HBsAg carriers. In the course of five years a total of 50% died. Formerly positive patients were, if CIEP was negative, examined also by the ELISA method. On examination by both methods 13 were negative (19.7%). Of the newly detected 14 carriers 7 suffered from cirrhosis of the liver, incl. five where examination of HBsAg revealed the disease. In eight patients the carriership was confirmed only by examination by the ELISA method. Of the latter five had previously alternately positive and negative results when examined by CIEP which indicates variations of the serum concentration of the antigen.

Aged↗

[Prediction of body height and shortening of the lower part of the body in adults with achondroplasia].

The authors present the method of predicting the body height of patients with achondroplasia in adulthood and the method of predicting shortening of the lower segment of the body as compared to the trunk. They evaluate a group of 12 patients with achondroplasia at the age from 3 to 17 years. They compare the growth curves of patients with normal Czechoslovak population and with a group of American patients suffering with achondroplasia. The application of growth curves of American patients with achondroplasia appears to be the most suitable and simple graphical method for the prediction of the body height of the Czechoslovak patients suffering from achondroplasia. The method of the prediction of dwarfism of the lower segment of the body has been developed for the purpose of the rational indication of the stepwise prolongation therapy by the compression-distraction method. Analogically it will be possible to verify the growth curves for some other bone dysplasiae presented in literature and predict dwarfism of the lower segment of the body in adulthood, e.g. in hypochondroplasia, metaphyseal chondrodysplasia of the type of Schmid, Turner syndromes, etc.

Achondroplasia↗

[Changes in the femoral neck in tabes dorsalis. Case report].

The authors analyze diagnostic and therapeutic problems in fractures associated with tabes dorsalis. In the foreground of the clinical picture are in the majority neurological symptoms. The first symptoms develop 15 years after the primary infection. The laboratory results are not decisive for the diagnosis. Previously treatment of these fractures was conservative in rare instances arthrodesis of the affected joint was performed. In the case-history the authors submit new therapeutic possibilities in fractures of the neck of the femur associated with tabes dorsalis, using total endoprostheses of the hip joint. The authors mention also possible complications. The subjective evaluation by the patient is, however, very favourable.

Arthropathy, Neurogenic↗