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R Kullenberg

Publications and source records attributed to R Kullenberg.

5 recordsLinked to original sources

[Technical improvements in bone densitometry].

The SBU-report no 127 "Mätning av bentäthet" [Measuring bone density] was published in 1995 and its conclusions are still valid. However, since then new treatment modalities have placed increasing demands on the diagnostic capability and performance of the apparatus used for bone densitometry. The most well-established and widely used technique for bone mineral determination is dual energy X-ray absorptiometry. Several international studies have shown that quantitative ultrasound should not be used for diagnosis or monitoring of osteoporosis. The reproducibility of one's method is important for monitoring, and the method's accuracy is important for diagnosis. Due to the limitations of the techniques and the slow turnover of the skeleton, repeated measurements are not meaningful until at least two years have passed. In order to maintain high quality in measurement results it is important to have trained personnel and to have a regular quality assurance program for the apparatus.

Absorptiometry, Photon↗

Determination of bone mineral density in the third lumbar vertebral body using photon absorptiometry techniques.

Dual-photon absorptiometry and triple-energy X-ray absorptiometry were used to investigate the total bone mineral content and density as well as the trabecular bone mineral density in the third lumbar vertebral body. Both anteroposterior (AP) and lateral (LAT) measurements were performed. By combining the two projections it was found that the mean trabecular bone mineral density for all 202 subjects included in the study was 52% (SD +/- 20%) of the total bone mineral density in the third lumbar vertebral body. The mean trabecular bone mineral density as a fraction of the total vertebral body bone mineral density decreased as a function of age. The relative annual change in this fraction differed between males and females. It was also found that neither trabecular nor total bone mineral density differed significantly between male and female subjects aged 25-35 years, and bone mineral density (BMD), expressed in g/cm3, showed no correlation to subject height, body weight or body mass index (BMI). Male and female individuals showed different rates of change of trabecular bone mineral density with age.

Absorptiometry, Photon↗

Measurement of bone mineral using multiple-energy x-ray absorptiometry.

Our laboratory has previously reported a method of determining the amount of bone mineral using triple-energy absorptiometry with a continuous x-ray spectrum. In the present study, the experimental properties of the technique were examined. The accuracy, the influence of fat content and body thickness and the in vitro and in vivo precision were analysed. The results found in this investigation showed that despite the complexity of the technique, the amount of bone mineral can be accurately determined. The in vivo precision was determined to be 3.4%, expressed as the coefficient of variation (CV), for different skeletal parts. The in vitro precision was found to be 2.1% (CV). Neither the fat content nor the body thickness had any effect on the measured bone mineral values. Excellent linearity and a close correlation were found between the true and the measured bone mineral values.

Absorptiometry, Photon↗

The feasibility of triple-energy absorptiometry for the determination of bone mineral, Ca and P in vivo.

The theoretical feasibility of triple-energy absorptiometry in general and the experimental conditions when using triple-energy absorptiometry for the determination of bone mineral, elemental calcium and phosphorus content in vivo have been investigated. A theoretical analysis of the decomposition of the mass attenuation coefficients is presented and discussed. The main obstacle to the effective use of triple-energy absorptiometry in vivo is the large number of pulses which must be detected to reduce the statistical fluctuations.

Absorptiometry, Photon↗