PubMed Health⌕ Search

Biomedical subjects

R L Bowen

Publications and source records attributed to R L Bowen.

At least 19 recordsLinked to original sources
PubMed1992

Dental composites/glass ionomers: the materials.

Most commercial dental composites contain liquid dimethacrylate monomers (including BIS-GMA or variations of it) and silica-containing compositions as inorganic reinforcing filler particles coated with methacrylate-functional silane coupling agents to bond the resin to the filler. They also contain initiators, accelerators, photo-initiators, photosensitizers, polymerization inhibitors, and UV absorbers. Durability is a major problem with posterior composites. The typical life-span of posterior composites is from three to 10 years, with large fillings usually fewer than five years. Polymerization shrinkage and inadequate adhesion to cavity walls are remaining problems. Some pulp irritation can occur if deep restorations are not placed over a protective film. Some have advocated the use of glass-ionomer cement as a lining under resin composite restorations in dentin. The concept of glass-ionomer cements (GICs) was introduced to the dental profession in the early 1970's. Current GICs may contain poly(acrylic acid) or a copolymer. Higher-molecular-weight copolymers may also be used to improve the physical properties of some GICs. Stronger and less-brittle hybrid materials have been produced by the addition of water-soluble compatible polymers to form light-curing GIC formulations. The ion-leachable aluminosilicate glass powder, in an aqueous solution of a polymer or copolymer of acrylic acid, is attacked by the hydrated protons of the acid, causing the release of aluminum and calcium ions. Salt bridges are formed, and a gel matrix surrounds the unreacted glass particles. The matrix is adhesive to mineralized tissues. Provisions must be made for maintenance of the water balance of restorations for the first 24 hours.(ABSTRACT TRUNCATED AT 250 WORDS)

Bisphenol A-Glycidyl Methacrylate↗
PubMed1992

Development of an adhesive bonding system.

Building on findings concerning adhesion to enamel, R L Bowen and his colleagues at the Paffenbarger Research Center, National Institute of Standards and Technology began addressing and solving problems associated with (1) silicate cements and unfilled resins, (2) bonding in an aqueous environment, and (3) the development of an adhesion system for both dentin and enamel that could withstand various stresses. This article reviews the development of an adhesion system for bonding dental composites to dentin and enamel.

Benzoates↗
PubMed1991

The effect of catalyst structure on the synthesis of a dental restorative monomer.

The addition product of 2-hydroxyethyl methacrylate (HEMA) and pyromellitic dianhydride (PMDA), known as PMDM, is a mixture of two structural isomers. The para PMDM isomer--currently used in mediating adhesive bonding of restorative materials to hard tooth tissues--is a crystalline solid. The meta isomer is a liquid. In the synthesis of PMDM, the para isomer, which can be purified by crystallization, is usually present to the extent of only 50% of the product mixture. The effect of the amine catalyst structure was studied relative to its role in increasing the yield of the para isomer, either by a reduction in the amount of the meta isomer or by an increase in the extent of overall reaction. The chemical structure of the amine catalyst had an important role in the synthesis of PMDM and influenced the ratio of the isomers. Among aliphatic amines, especially noteworthy as catalysts that gave excellent yields of the para isomer in high purity were N,N-di-isopropyl-ethylamine and hexamethylenetetramine.

Adhesives↗
PubMed1991

Protective coatings for tooth crowns.

Transfer of technology to the dental office could provide thin polymeric coatings over tooth crowns and accessible root surfaces. These coatings can be prepared from relatively inexpensive, commercially available materials in one-step reactions. When the monomer technique becomes available, it will provide caries protection for all of your patients.

Benzoates↗
PubMed1989

Pulpal and micro-organism responses to two experimental dental bonding systems.

Several new bonding systems have been reported that promote strong adhesion. This in vivo study involves treatment with two experimental bonding systems of Class V cavity preparations in the teeth of three Macaca fascicularis primates and reports the pulpal responses and degree of micro-organism invasion associated with each treatment. In each monkey, the teeth in the upper left quadrant were treated with the experimental solution, containing 2.5% aluminum nitrate + 1.5% oxalic acid + 4.9% NPG, followed by application of PMDM and Silux XL composite. The lower right quadrant was treated with the experimental solution, containing 5.7% NPG + 2.4% nitric acid, followed by PMDM and Silux XL composite. The upper right and lower left quadrants were treated with clinical materials to establish positive and negative controls. After four, 25, and 59 days, the teeth were removed and underwent routine histological and bacteriological evaluation. Slight pathological conditions were noted for superficial and deep responses, but all values approached 0.0 by the 59th day. Micro-organisms were seen under only 12% of the restorations. Both experimental systems appear to be safe for human clinical trials.

Animals↗
PubMed1989

Mechanically-induced generation of radicals in tooth enamel.

Mechanical instrumentation of enamel leads to the formation of long-lived free radicals that can be conveniently measured by electron paramagnetic resonance (EPR) spectroscopy. Powdered enamel tissue exhibited EPR signals remarkably similar to the radicals formed by ionizing radiation. The observations described below lead to the conclusion that physical stress will induce a free-radical formation in dental tissues. These observations have significance for other areas of study such as dosimetry and archeological dating.

Dental Enamel↗
PubMed1989

An in vitro investigation of the effects of glass inserts on the effective composite resin polymerization shrinkage.

We placed an MOD preparation in each of 12 permanent molars, then restored each tooth with a posterior composite resin by means of six different application techniques (I-polymerization as one complete unit; II--polymerization as one complete unit with glass inserts; III--polymerization in gingivo-occlusal increments; IV-polymerization in gingivo-occlusal increments with glass inserts; V--polymerization in bucco-lingual increments; and VI--polymerization in a gingival increment with glass inserts, then bucco-lingual increments). A precision strain gauge was attached to the buccal surface of each tooth and balanced at zero. After each increment was polymerized, the strain appearing on the strain gauge indicator was recorded. Each tooth was restored by use of all techniques; two teeth started with each technique. Results demonstrated the average microstrain units to be 127-I, 102-II, 105-III, 86-IV, 72-V, and 66-VI. A randomized block design was the format used for data evaluation. Scheffé's Test indicated that composite resin placement and polymerization in bucco-lingual increments (V) created significantly less cuspal deflection than polymerization as one complete unit, with or without glass inserts (I and II), p less than 0.001, and gingivo-occlusal increments (III), p less than 0.05. Placement and polymerization in a gingival increment with glass inserts, then bucco-lingual increments (VI), also created significantly less internal deflection than polymerization as one complete unit, with or without glass inserts (I and II), p less than 0.001, and gingivo-occlusal increments (III), p less than 0.005.

Analysis of Variance↗
PubMed1989

Substitutes for N-phenylglycine in adhesive bonding to dentin.

Using bond strength measurements, we investigated a number of related compounds in order to elucidate the role of the surface-active ingredient, N-phenylglycine (NPG), in experimental two-step and three-step bonding protocols resulting in adhesive bonding to dentin. All active compounds identified for the two-step or the three-step protocol were N-aryl-alpha-amino acids, and the results delineate some of the key features of the NPG molecule for bonding. For the three-step protocol, there was a requirement for a secondary or tertiary aromatic amino group, a carboxylic acid group, and a single (secondary or tertiary) methylene unit between those two functional groups of the amino acid. For the two-step protocol, additional substitutions at the para position of the phenyl ring on the amine improved the bond strength. In both protocols, para-methyl- and para-chloro-substituted NPG analogues ranked higher than NPG. A "catalytic" effect of the aromatic tertiary amino group on the polymerization of the adhering resin in both procedures could not be ruled out.

Adhesiveness↗
PubMed1989

Clinical biocompatibility of an experimental dentine-enamel adhesive for composites.

Previous studies have shown that sequential application of an acidified solution of ferric oxalate, N-phenylglycine and PMDM (the reaction product of pyromellitic dianhydride and hydroxyethyl methacrylate) yields strong adhesive bonding of composite resins to both dentine and enamel. The purpose of this study was to evaluate the clinical characteristics and the biocompatibility of this system in human teeth scheduled for extraction in the course of orthodontic treatment. Controls were light-cured Scotch-bond or ZOE in contralateral teeth. Evaluation criteria, which included clinical feasibility, patient acceptability, retention, margin aesthetics and human pulp response, were met. Within the 4-241 day observation periods, there was no postoperative sensitivity, pain, loss of retention, staining or discolouration. All pulp responses (double-blind pulp analysis including all teeth) were acceptable. With mean (+/- SD) remaining dentine thickness (RDT) of 0.67 +/- 0.35 mm, all indicators of pulp inflammation (displacement, superficial response, deep response etc.) averaged between none and slight, under 1 on a 0-4 scale. Both controls gave similar results. Linear regression analysis indicated low responses at all RDTs. The experimental material is safe and effective; further unrestricted clinical evaluations in teeth to be retained are indicated.

Adhesives↗
PubMed1988

Adhesion to dentin by means of Gluma resin.

In its present version, the Gluma system for bonding restorative resin to dentin involves the application of an enamel bonding agent prior to the composite resin. Conceivably, pretreating the dentin with solutions of amino acids, and incorporating camphorquinone and selected methacrylic monomers into the Gluma adhesive would nullify the need for the enamel bonding agent. A bond strength to dentin of 13.4 MPa was obtained in the control experiment. Using a solution of pyruvic acid and glycine as pretreatment, and an optimized adhesive mixture containing glutaraldehyde, HEMA, BIS-GMA, camphorquinone, and water, bond strengths to dentin of 14.5 MPa and to enamel of 23.3 MPa were obtained. Thus, the new Gluma bonding system gave acceptable bond strengths without the prior application of enamel bonding agents.

Adhesiveness↗