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Biomedical subjects

R L Curry

Publications and source records attributed to R L Curry.

8 recordsLinked to original sources
PubMed1989

Beverage alcohol spending in Singapore: a potential development constraint?

World Health Organization sponsored studies identify Singapore as a low-level-drinking country where beverage alcohol consumption is not growing at a rapid pace. However, data for Singapore do show that from 1978 through 1986, consumer spending on beverage alcohol was on the rise, although not alarmingly. Growing spending on beverage alcohol could signal a challenge to Singapore's continuing economic development when viewed in the context of the country's emerging labor shortage and its development strategy. Beverage alcohol could become a problem due to the upward trend in spending on drinking, the emergence of a labor shortage, and the need for the largest possible pool of highly skilled workers to sustain Singapore's growth and development. Government might, therefore, look into spending on alcohol as diligently as it focuses on the consumption of tobacco and narcotics.

Alcoholic Beverages↗
PubMed1974

Serological studies with purified neuraminidase antigens of influenza B viruses.

Neuraminidase (N) can be extracted from virus particles of influenza B strains by treatment with trypsin, in a form which is free from the viral HA and has specific immunological activity. The N antigen of B/LEE/40 behaves differently from that of 1965-6 strains in gel diffusion and enzyme inhibition tests with animal antisera raised by infection or by artificial immunization with the homologous or heterologous strains. The frequency and titres of NI antibody detected in human sera by B/LEE antigen are different from those found with antigen from B/Eng/13/65. The latter antibody appears to contribute to the effect of serum HI antibody in protecting volunteers exposed to a deliberate intranasal challenge infection of the B/Eng/13/65 strain.

Animals↗
PubMed1973

The efficacy of live and inactivated vaccines of Hong Kong influenza virus in an industrial community. A report to the Medical Research Council Committee on influenza and other respiratory virus vaccines.

Intranasal vaccines of inactivated or living attentuated A2/Hong Kong influenza viruses were compared for clinical acceptability, serological effects and protective efficiency against natural epidemic influenza in a large industrial and clerical population.Neither vaccine resulted in any significant untoward side-effects. The serum haemagglutination-inhibiting (HI) antibody response within 1 month of vaccination was similar with both vaccines; approximately 50% of those with little or no pre-vaccination antibody developed 4-fold or greater rises in titre. The effect of the antigenic potency of the vaccines and the prior immunological experience of the population is discussed. Volunteers given live vaccine showed a 2.2-fold lower incidence of clinical influenza than those given killed vaccine in a natural epidemic 16 months after vaccination.

Antibody Formation↗
PubMed1972

The role of serum haemagglutination-inhibiting antibody in protection against challenge infection with influenza A2 and B viruses.

The intranasal inoculation of volunteers with living partially attenuated strains of influenza A and B viruses offers a new opportunity to determine the protective effect of serum haemagglutin-inhibiting antibody against a strictly homologous virus, under conditions where the time and dosage of the infective challenge can be controlled, the scoring of proven infections can be more precise and higher rates of infection can be achieved than in most natural epidemics.In 1032 adult volunteers, whose serum HI antibody titre was determined immediately before virus challenge, there was a consistent inverse quantitative relationship between the HI titre and the likelihood of infection. The PD 50 (50% protective dose) of HI antibody was 1/18-1/36, but an unusual finding was that volunteers with no detectable pre-challenge antibody often seem to be less susceptible to infection than those with pre-challenge antibody in low titre.In one group of volunteers challenged with an influenza B strain there was no evidence that pre-challenge antibody titres against viral neuraminidase had any significant protective effect against challenge infection.

Administration, Intranasal↗
PubMedDate not supplied

Using videorecordings in pediatric nursing practice.

This article explores the innovative uses of videorecordings in pediatric nursing practice. Social learning theory and primary nursing concepts provide the conceptual orientation. Creative uses of videorecordings include: enhanced family education; continuity of care through caregiver modeling and staff communication; audiovisual progress recording; and potential behavioral development in the pediatric client. Suggestions regarding technical aspects of videorecordings in the clinical area may facilitate videorecording application.

Child↗