Sir William Osler--Abroad with Jane.
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Biomedical subjects
Publications and source records attributed to R L Golden.
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Sir William Osler is one of the most admired and honored physicians in the history of medicine. He influenced the development of medicine in Canada, the United States, and Great Britain, where he held professorships at McGill University, the University of Pennsylvania, Johns Hopkins University, and Oxford University. Through his textbook, The Principles and Practice of Medicine, and other clinical and philosophical writings, he exercised a truly global influence. In this sesquicentennial of his birth, William Osler continues to serve as a model of excellence for the medical profession. This examination of the reasons for his enduring impact reveals a legacy of clinical, scientific, literary, educational, and intraprofessional accomplishments linked to a remarkable personality, and bound together by an extraordinary humanism.
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Aneurysms of the hypogastric artery are rare occurrences that are frequently asymptomatic until the time of rupture. When signs and symptoms are present, a pulsatile pelvic mass, frequently detected by rectal or vaginal examination, may produce compression symptoms with urologic, gastrointestinal, and neurologic manifestations. In addition to classical invasive methods of detection such as angiography, newer noninvasive imaging techniques, including ultrasonography, computerized tomography, and magnetic resonance imaging, may be employed to establish the diagnosis. Proximal ligation of the hypogastric artery is the usual method of treatment. A case of bilateral, giant hypogastric artery aneurysms with successful surgical management is reported.
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Tuberculosis of the skin resulting from direct inoculation of a tuberculin-sensitive individual (tuberculosis verrucosa cutis) is a rare disease first described by Laennec. Various terms, including prosector's wart and the anatomical tubercle, have been used to describe these lesions, which were often acquired in the autopsy room. The disease usually remains local in those patients with acquired immunity from previous infection with tuberculosis. Sir William Osler possessed an abiding interest in pathology throughout his career and performed nearly 1,000 postmortem examinations. He describes the acquisition of numerous prosector's warts and their evolution and treatment. It is postulated that Osler was a tuberculin-sensitive individual at the time he acquired his anatomical tubercles. His contributions to dermatology are discussed.
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The life of William Osler, MD, spanned three nations and two continents and left an enduring and universal impact on medicine. Osler held professorships during his career in Montreal, Philadelphia, Baltimore, and Oxford. His achievements great and small during these periods have been medallically commemorated both in his lifetime and posthumuously. The most famous of these portrayals is the Vernon plaque created in Paris at the turn of the century, of which many replicas and variants have been produced. The historical associations of these medallic tributes are relevant to better understanding of certain aspects of Osler's life and elucidating those unusual qualities of mind and character that made him unique.
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