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R L Hackett

Publications and source records attributed to R L Hackett.

79 records · Page 5Linked to original sources

Gadolinium-DTPA enhancement of VX-2 carcinoma of the rabbit kidney on T1 weighted magnetic resonance images.

Experimental renal carcinoma was induced by percutaneous injection of VX-2 carcinoma cells into the left kidney in New Zealand white rabbits. Magnetic resonance imaging (MRI) was performed at 0.15 T before and after intravenous injection of 0.3 mmol gadolinium-DTPA (Gd-DTPA) per kg body weight. Gd-DTPA enhanced the tumors by increasing the signal intensity on T1 weighted images. The enhancement was evident immediately after Gd-DTPA injection, increasing during the observation time of 30 minutes. Histologically the areas of enhancement corresponded well to the viable tumor tissue.

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