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R L Hooper

Publications and source records attributed to R L Hooper.

6 recordsLinked to original sources
PubMed2000

Measurement of quality of life in alcohol-dependent subjects by a cancer symptoms checklist.

There are few studies of Quality of Life measures (QoL) in alcohol-misusing patients. The present study addresses this deficiency. The sample consisted of 60 (39 men, 21 women) alcohol dependent subjects defined by DSM-IV criteria (American Psychiatric Association, 1994). At baseline (4-5 days after admission and detoxification) sociodemographic data were collected, and three questionnaires were administered: the Rotterdam Symptoms Checklist (RSCL), the Severity of Alcohol Dependence Questionnaire (SADQ), and Alcohol Problems Questionnaire (APQ). QoL scores for dependent alcoholics both for physical and psychological measures were significantly worse (higher) than those reported for a variety of cancer patients. Psychological symptom scores were higher than physical symptoms at baseline. Correlations of RSCL scores to both SADQ and APQ were greater for RSCL physical compared to psychological symptom scores. The subjects were followed up at 12 weeks when the RSCL was re-administered and relapse status ascertained. Fifty-eight (97%) subjects were successfully contacted at 12 weeks of whom 36 (62%) had relapsed. After a repeated measures ANOVA psychological and physical symptom subscores were statistically significantly improved as a result of not relapsing to heavy drinking. There was no significant change in scores in the relapse group when baseline and week 12 scores were compared. The RSCL measure is a useful QoL assessment tool in alcohol-dependent subjects.

Adult↗
PubMed1989

Efficacy of diethyl methylbenzamide (deet) against Aedes dorsalis and a comparison of two end points for protection time.

The repellent deet (N,N-diethyl-3-methylbenzamide) was tested against the mosquito Aedes dorsalis in a coastal salt marsh in California. The experimental design incorporated a multiple regression model, sequential treatments and a proportional end point (95%) for protection time. The ED95 (95% effective dose) and 4-h ED95 were estimated at 0.05 mg/cm2 and 0.09 mg/cm2, respectively. The 0.05 mg/cm2 protection time and 0.10 mg/cm2 protection time were estimated at 0.2 h and 4.4 h. The decay constant and half-life were estimated at 0.17 h-1 and 4.1 h. The design and analysis of repellent field trials are discussed.

Aedes↗
PubMed1989

A field trial of ethyl hexanediol against Aedes dorsalis in Sonoma County, California.

The repellent ethyl hexanediol (2-ethyl-1,3-hexanediol) was tested against the mosquito Aedes dorsalis in a coastal salt marsh in California. The experimental design incorporated a linear regression model, sequential treatments and a proportional end point (95%) for protection time. The protection time of 0.10 mg/cm2 ethyl hexanediol was estimated at 0.8 h. This time is shorter than that obtained previously for deet (N,N-diethyl-3-methylbenzamide) against Ae. dorsalis (4.4 h).

Aedes↗
PubMed1979

Lipid and salt effects on carbocyanine dye-induced photo-voltages in bilayer membranes.

Voltage transients induced by flash illumination of bilayer membranes with sorbed dye, 3,3' -dimethyl-2,2' -oxacarbocyanine chloride (diO-C1-3-CI), vary with membrane lipid composition and aqueous solution salt concentration. The voltage transients are probably induced by physical movements of sorbed dye molecules following photo-isomerization. Increased salt (NaCl and NaBr) concentrations in the aqueous solutions reduced the photo-voltage amplitudes by reducing the amount of dye sorbed to the membranes, and by decreasing the effective membrane thickness. The photo-voltage risetimes and falltimes varied systematically with salt concentration and membrane lipid composition, reflecting structural changes in the membrane's surface layer.

Carbocyanines↗