Sternal mass in a patient with Paget's disease.
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Biomedical subjects
Publications and source records attributed to R L Hutto.
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A unique case in which a berry aneurysm was observed to rupture during computed tomography scanning of the brain is reported. Two earlier case reports of aneurysmal rupture during computed tomography scanning are reviewed, followed by a discussion of possible mechanisms of rupture during contrast studies. Contrast medium infusion may have the potential to cause aneurysmal rupture by a direct anticoagulant effect, by affecting the endothelial membrane, by interacting with platelet release of vasoactive substances, by inducing vasodilation, by removing the protective arterial spasm, or by other unexplored mechanisms. The information to be gained by infusion of contrast medium in cases of aneurysmal rupture can be significant and the rarity of rerupture during contrast medium infusion does not appear to pose a significant risk in the vast majority of cases.
Cardiac disease is present in approximately 30% of children with stroke. Other case reports have documented stroke in patients who have previously undergone the Fontan procedure for correction of tricuspid atresia. Most of these strokes have occurred in the immediate postoperative period. There has been one report of a cerebral infarction 3 1/2 months after surgery. We report a child with superior cerebellar artery distribution infarction after undergoing the Fontan procedure 24 months previously. Previous reports of stroke in patients having undergone the Fontan procedure and possible etiologies for these strokes are discussed. We believe our patient had the longest procedure-to-stroke interim yet reported.
Pituitary enlargement as a result of hypothyroidism is a well recognized entity with several reports over the last decade. Hypothyroidism is only rarely recognized as a cause of basal ganglia calcifications, despite several large computer tomography (CT) studies. We present a case of primary hypothyroidism in which both pituitary hyperplasia and basal ganglia calcifications were observed in a young female who presented with hyperprolactinemia. Hypothyroidism should always be considered in the evaluation of hyperprolactinemia.