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Biomedical subjects

R L Jenkins

Publications and source records attributed to R L Jenkins.

At least 163 records · Page 9Linked to original sources

Recovery of cognitive abilities in male alcoholics.

Recovery of cognitive functioning in male alcoholic patients during 3 months abstinence was assessed using a shortened version of the Wisconsin Card Sorting Test (WCST). Twenty-four alcoholic patients were tested after 2 to 3 weeks of sobriety and at 11 to 12 weeks post-drinking, while a second group of 24 alcoholic patients was tested only after 11 to 12 weeks of sobriety. A control group of 24 healthy males also received the WCST. After 3 weeks of sobriety, alcoholic patients completed significantly fewer categories and made more errors than control subjects. Alcoholic patients also made more perseverative response than did controls. At 12 weeks post-drinking, the performance of alcoholic subjects was intermediate to that of controls and to alcoholic patients tested following 3 weeks of abstinence and did not differ significantly from either group. The results suggest that following the acute withdrawal period alcoholic patients experience difficulties in conceptual abilities and in the capacity to shift cognitive sets when appropriate. After nearly 3 months of abstinence, partial but not complete recovery of these abilities is evident.

Adult↗

Chlorination of benzidine and other aromatic amines an aqueous environments.

The fate of aniline, N,N-dimethylaniline and benzidine in chlorinated waters was investigated. Conditions were controlled to approximate the process chlorination of raw water supplies and wastewater secondary effluents. As the molar ratio, (Cl2)/(amine), was increased, amine depletions increased and leveled off at about (Cl2)/(amine) = 1. Depletions in distilled water with "free" chlorine were somewhat higher than those in activated sludge/secondary effluent with combined chlorine. For each amine the number and type of products appeared to be independent of the water matrix and the ratio, (Cl2)/(amine). For the monophenyl amines ring chlorination was a significant depletion pathway. Extended chlorination of aniline yielded a precipitated product, while the N-substituted amine, N,N-dimethylaniline did not yield a solid product. In contrast to the monophenyl amines, when benzidine (p,p'-diaminobiphenyl) was exposed to chlorinated waters, a solid product resulted immediately. Infra-red analysis of this product indicated a polymeric structure with no ring chlorination. GLC analysis of the chlorination supernatant showed no ring substituted isomers of benzidine.

Aniline Compounds↗