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Biomedical subjects

R L Mace

Publications and source records attributed to R L Mace.

3 recordsLinked to original sources
PubMed1998

Universal design in housing.

Universal design in housing is a growing and beneficial concept. It is subtle in its differences from barrier-free, accessible, and industry standard housing. Accessibility standards and codes have not mandated universal design and do not apply to most housing. Universal design exceeds their minimum specifications for accessible design and results in homes that are usable by and marketable to almost everyone. Universal homes avoid use of special assistive technology devices and, instead, incorporate consumer products and design features that are easily usable and commonly available.

Architectural Accessibility↗
PubMed1995

Seroresponse to trivalent oral poliovirus vaccine as a function of dosage interval.

Seroresponses to trivalent oral poliovirus vaccine are not uniform throughout the world. Definition of the variables that determine successful immunization is vital to ensure global polio eradication. One such variable may be dosage interval. To investigate this effect 108 infants were enrolled in a clinical trial and randomly assigned to receive three doses of trivalent oral poliovirus vaccine (standard United States formulation) at 2, 3 and 4 or 2, 4 and 6 months of age. After three doses of vaccine given before 6 months of age, immunity was virtually complete for each of the three poliovirus types in both groups. After two doses the seroresponse rate to each type was less with the shorter dose interval. However the difference was not significant (P = 0.15) in the sample size studied. Such responses differ markedly from those seen in developing countries, where four or more doses of vaccine may fail to provide complete protection. Differences other than dosage interval must contribute to those failures.

Antibodies, Viral↗