Retrograde coronary sinus cardioplegia in redo aortocoronary bypass.
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Cardioplegic Solutions↗
Biomedical subjects
R L McKowen
Publications and source records attributed to R L McKowen.
Extended aortic root replacement with aortic allografts.
Complex left ventricular outflow tract obstruction after operation for subaortic stenosis or with hypoplastic aortic anulus remains a challenge for pediatric cardiac surgeons. We have recently applied a new technique of extended aortic root replacement using a cryopreserved aortic allograft to treat two patients who had previously been operated on for subaortic stenosis and a third who had aortic stenosis with a hypoplastic aortic anulus. This new procedure combines the concept of aortoventriculoplasty with aortic root replacement and coronary artery reimplantation. The valved aortic homograft is used in place of an aortic valve prosthesis and the attached anterior mitral leaflet augments the interventricular septum to relieve the subvalvular left ventricular outflow tract obstruction. The coronary ostia are then reimplanted into the allograft and an anastomosis between the distal graft and the ascending aorta is completed. Allograft aortic tissue is then used to patch the right ventricular outflow tract. One patient had aortic stenosis with annular hypoplasia and did well after extended root replacement. Two patients had previous operations for subaortic stenosis before undergoing extended aortic root replacement. One required mediastinal exploration and drainage at 2 weeks for Serratia marcescens mediastinitis and bacteremia, but uncomplicated recovery followed. The other patient had complete heart block for 2 days, but normal sinus rhythm resumed and convalescence was benign. This modified technique with the aortic allograft was very helpful in treating these difficult problems, and the lack of mortality, limited morbidity, and good functional results are encouraging.
Adolescent↗
Infectious complications and cost-effectiveness of open resuscitation in the surgical intensive care unit after cardiac surgery.
From July, 1982, to May, 1984, 2,412 patients underwent cardiac surgery. Open resuscitation through a midline sternotomy was performed in the surgical intensive care unit (SICU) 88 times in 64 patients one minute to 10 days after admission. There were 49 initial survivors; 31 patients had primary closure in the SICU (Group 1), and 18 patients had delayed closure (Group 2). In Group 1 there was 1 death. Wound infection developed in 2 of the 30 survivors--Escherichia coli in 1 and Staphylococcus epidermidis in 1. The latter required subsequent debridement. In Group 2 there were 8 survivors and no wound infections. Fifteen patients could not be resuscitated because of ventricular arrhythmia (13%), asystole (33%), cardiogenic shock (47%), and tamponade (7%). Only 2 of 38 patients, or 5%, experienced wound infections. This study demonstrates that open resuscitation in the SICU is a safe, rapid, and cost-effective procedure that will allow earlier intervention, diagnosis, and treatment. In no instance was death attributed to wound infection, and at our institution, this method resulted in cost savings of more than $1,000 per patient.
Adult↗