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Biomedical subjects

R L Simpson

Publications and source records attributed to R L Simpson.

At least 37 records · Page 2Linked to original sources

Medical errors, airplanes, and information technology.

The IOM says tens of thousands die each year from medical errors. Learn lessons from the aviation industry and how we can build a culture of safety with information technology and clinical information systems.

Accidents, Aviation↗

Nurses--yes, nurses--improve physician order entry.

Automated physician order entry systems can reduce medication errors and improve patient outcomes. But there are a variety of barriers--psychological, behavioral and technological--to physician adoption. Nursing not only has a stake in this issue, but plays a valuable role in resolving it.

Forms and Records Control↗

Stop the rise in nursing errors--systematically.

The number of reported nursing errors in hospitals has increased in each of the past 5 years. Information technology can help nurses make better care decisions in today's harried hospital environment.

Decision Support Systems, Clinical↗

Nursing a merger.

Explore the source record for details and available documents.

Contract Services↗

Safety of losartan in hypertensive patients with thiazide-induced hyperuricemia.

BACKGROUND: Losartan, an angiotensin II receptor antagonist, has been shown to decrease serum uric acid and to increase urinary excretion of uric acid. METHODS: To determine if this effect can increase the risk of acute urate nephropathy, 63 hypertensive patients with thiazide-induced asymptomatic hyperuricemia (serum uric acid 7.0 to 12.0 mg/dl) were randomized double-blind to losartan 50 mg every day (q.d.), losartan 50 mg plus hydrochlorothiazide (HCTZ) 50 mg q.d., HCTZ 50 mg q.d., or placebo for three weeks. To potentiate the risk of crystal formation, patients received a 2 g/kg protein diet one day prior to each clinic visit on days 0 (baseline), 1, 7, and 21. RESULTS: Adverse events typically associated with acute urate nephropathy, for example, flank pain, hematuria, or increased blood urea nitrogen/creatinine, were not reported. Uric acid excretion and urine pH increased four and six hours after losartan on day 1 compared with day 0. Dihydrogen urate, the primary risk factor for crystal formation, decreased at four and six hours on day 1 compared with day 0 associated with the concurrent rise in urine pH. Day 7 and 21 changes, compared with day 0, in uric acid excretion rate, urine pH, and dihydrogen urate with losartan were comparable to day 1 results but were not statistically significant. Serum uric acid was significantly reduced after 21 days of therapy with losartan. CONCLUSION: Losartan decreased serum uric acid and increased uric acid excretion without increasing urinary dihydrogen urate, the primary risk factor for acute urate nephropathy, during 21 days of dosing in hypertensive patients with thiazide-induced hyperuricemia.

Adult↗

Changing world, changing systems: why managed health care demands information technology.

In an industry in which the only constant is change, information technology is increasingly becoming the means by which health care organizations manage the constant volatility they face. This article discusses the emerging managed care trends that are driving the move to open systems and increased technological flexibility. In addition, it explains how changing models of care are fueling the evolution of a new breed of clinical information systems that are interdisciplinary, interoperable, and outcomes focused.

Hospital Information Systems↗

Let's talk telemetry.

As telemetry becomes more prevalent, the lines between medical device and clinical information system begins to blur. The author explains why telemetry is growing and merging with traditional information systems and the issues this creates.

Hospital Information Systems↗

Nursing's role in Y2K planning.

Why haven't more nurses fulfilled their role in Y2K planning? Nurses need to apply their skills and expertise to solving often overlooked problems such as point-of-service applications, transactions with business partners, and contingency planning.

Chronology as Topic↗