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R L Snipes

Publications and source records attributed to R L Snipes.

7 recordsLinked to original sources

Anatomy of the cecum of the dwarf hamster (phodopus sungorus).

The cecal anatomy of the dwarf hamster, Phodopus sungorus, was investigated macroscopically and at the light, transmission electron microscopic and scanning electron microscopic levels. In addition, the arterial supply to the cecum and connecting mesenteries were elucidated. The cecum is divisible into an ampulla ceci and a corpus ceci. In the former, the differentiation of the ileocecal orifice and circumventing fold is described. Scanning electron microscopically, the surface topography of the cecum appears as ring-walled elevations with a central depression and looped configurations, which correlate light microscopically to a "rolling-hills" type mucosa with wide-opened crypts. This type of mucosa is set in contrast to the classically described large intestinal mucosa in man and some other mammals. The present observations are compared with descriptions made on the cecum of the common field vole, Microtus agrestis, also a myomorph but belonging to another subfamily.

Animals

Anatomy of the cecum of the vole, microtus agrestis.

The anatomy of the cecum of the vole, Microtus agrestis, was investigated using macroscopic dissections, "wet" and dried total specimens, and correlated light, scanning and electron microscopy. The cecum of the vole reveals a series of structural differentiations including a mural lip in the ampulla ceci and a spiral fold in the corpus ceci. The mucosa covering the cecal wall possesses short, wide-opened crypts and differs from the classical descriptions of the large intestinal mucosa. Fine structural observations suggest the cecal epithelium to be capable of active absorption. The morphological findings are correlated with the herbivorous habit of the vole and compared with observations in the rabbit and other rodents.

Animals

Anatomy of the rabbit cecum.

The anatomy of the rabbit cecum was investigated using macroscopic dissections, vascular injections, dried total specimens, light microscopy, and scanning and electron microscopy. The morphology of the three portions of the cecum (ampulla coli, corpus ceci and appendix vermiformis) is described. For comparison, the proximal colon, ileum and sacculus rotundus were also investigated. The thickness of the different layers of the intestinal wall of each area was measured. The arterial supply and mesenteries of the cecum were also studied. The rabbit cecum represents structurally a highly developed organ.

Animals

Morphological appearance of fat in the epithelial cells of different portions of the intestines in mice.

Absorption of administered fat in the small intestine of mice as judged morphologically in semi-thin sections demonstrates a proximal to distal gradient, being greatest in the mid-jejunal area, but less in the duodenum and ileum. The criterion of the amount and size of fat droplets in intestinal epithelial cells, however, does not necessarily give a reliable indication of the efficiency of fat absorption in the different segments of the intestine.

Adipose Tissue

Limited fat absorption in the large intestine of mice. A morphological study.

A limited fat-absorbing ability of the epithelial cells in the cecum and colon of mice was demonstrated light- and electron-microscopically. After injection of predigested donor fat into ligated segments of the large intestine and after massive gastric intubation of fat, fat droplets, predominantly of extremely large diameter, were visible in the cecum and colon. Comparison with fat absorption in the proximal and distal small intestine was undertaken. The large intestine, similar to the distal small intestine, is capable of absorbing lipids; however, the subsequent processing of fat appears considerably less effcient than in the proximal segments of the small intestine.

Animals